PMID: 15357181Sep 11, 2004Paper

Statistical pixelwise inference models for planar data analysis: an application to gamma-camera uniformity monitoring

Physics in Medicine and Biology
A KalemisR J Ott

Abstract

In this paper two tests based on statistical models are presented and used to assess, quantify and provide positional information of the existence of bias and/or variations between planar images acquired at different times but under similar conditions. In the first test a linear regression model is fitted to the data in a pixelwise fashion, using three mathematical operators. In the second test a comparison using z-scoring is used based on the assumption that Poisson statistics are valid. For both tests the underlying assumptions are as simple and few as possible. The results are presented as parametric maps of either the three operators or the z-score. The z-score maps can then be thresholded to show the parts of the images which demonstrate change. Three different thresholding methods (naive, adaptive and multiple) are presented: together they cover almost all the needs for separating the signal from the background in the z-score maps. Where the expected size of the signal is known or can be estimated, a spatial correction technique (referred to as the reef correction) can be applied. These tests were applied to flood images used for the quality control of gamma camera uniformity. Simulated data were used to check the validit...Continue Reading

References

Aug 1, 1976·The British Journal of Radiology·N J Cox, B L Diffey
Aug 31, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·K M PeterssonA P Holmes
Aug 31, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·K M PeterssonA P Holmes
Mar 22, 2002·NeuroImage·Christopher R GenoveseThomas Nichols
May 28, 2003·Human Brain Mapping·Terry L JerniganArne L Ostergaard
Dec 20, 2003·NeuroImage·Satoru Hayasaka, Thomas E Nichols

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Citations

Aug 10, 2011·Journal of Biomechanical Engineering·Martin L TanakaLaurel Kuxhaus
Feb 8, 2013·Journal of Biomechanical Engineering·Kevin L TroyerChristian M Puttlitz
Nov 9, 2006·Medical Physics·James M BrindleWesley E Bolch
Sep 21, 2007·Medical Physics·Chester R RamseyMartha Mitchell
Jun 8, 2004·Violence and Victims·Patti A Fritz, K Daniel O'Leary
Mar 31, 2005·Physics in Medicine and Biology·Dale L Bailey, Antonis Kalemis

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