Statolon-induced resistance of mice to mengovirus.

Applied Microbiology
J P Schmidt, F F Pindak

Abstract

Mice receiving statolon intraperitoneally were 1,000 times more resistant to intraperitoneal challenge with mengovirus than were untreated controls. Protection was afforded when statolon was administered 1 day before or 1 day after intraperitoneal inoculation with the virus. No therapeutic effect was observed when treatment with statolon was delayed for 2 days or more after virus infection. Exposure of mice to a simulated space cabin environment did not increase their susceptibility to the lethal effects of mengovirus infection or eliminate the protective effect of statolon.

Citations

Mar 1, 1968·Applied Microbiology·J P Schmidt, F F Pindak
Jul 1, 1968·Applied Microbiology·F F Pindak
Oct 1, 1968·Applied Microbiology·K Y Huang, F B Gordon
Aug 1, 1969·Applied Microbiology·F F PindakJ Z Kendrick

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