Status epilepticus: a review, with emphasis on refractory cases

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
Gary Hunter, G Bryan Young

Abstract

Status epilepticus is among the most dramatic of clinical presentations encountered by emergency room physicians, neurologists, neurosurgeons and intensivists. While progress in its management has been aided significantly with an increasing number of effective treatment options, improved diagnostic methods and more effective monitoring, poor outcomes and diagnostic failures are still frequently encountered. Refractory cases still carry significant morbidity and mortality rates, including poor cognitive outcomes. This review discusses basic pathophysiology and management of status epilepticus, neuroimaging findings, the role of continuous electroencephalogram monitoring and nonconvulsive status epilepticusas well as recent developments in treatment options for refractory cases.

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Citations

Oct 24, 2013·Journal of Neurology·José L Fernández-TorreMiguel A Hernández-Hernández
Nov 10, 2013·PLoS Computational Biology·Maryam M ShanechiEmery N Brown
Feb 13, 2014·Neurocritical Care·F A ZeilerM West
Mar 1, 2015·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·G Bryan Young, Kristin M Ikeda
Jan 13, 2015·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Frederick A ZeilerMichael West
Jun 26, 2015·Expert Review of Neurotherapeutics·Yafei ShangguanXuefeng Wang
Nov 13, 2015·Expert Review of Neurotherapeutics·José L Fernández-TorreMiguel A Hernández-Hernández
Apr 7, 2021·Toxicology and Applied Pharmacology·Ariel GoreShlomi Lazar

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