Stem cells and differentiation--a synoptic review of patents granted since 2009

Expert Opinion on Therapeutic Patents
Poornima SureshkumarAgapios Sachinidis

Abstract

Innovations in human pluripotent stem cell research and their application in therapeutics have seen a giant leap in the past decade. Patent applications related to human pluripotent stem cell generation, culture and differentiation show an ever-increasing trend worldwide with hundreds of patents being applied for every year. With the turn of the second decade in stem cell patenting, a review of the latest patents issued will be significant. The growing need in healthcare sector has revolutionized stem cell application in clinical therapeutics by extending in unprecedented dimensions. With the potential of being able to differentiate into any desired adult cell lineage, human pluripotent stem cells find a wide range of applicability in clinical as well as cosmetic therapy. Moreover, the recent innovation of isolating a disease-specific pluripotent stem cell has opened new horizons to stem cell application in cell therapy. This review gives an overview of significant international patents granted on innovations in human pluripotent stem cell differentiation methodologies between 2009 and 2014. The discovery of human pluripotent stem cells and their immense potential in clinical therapeutics has increasingly channeled scientific r...Continue Reading

References

Nov 6, 1998·Science·J A ThomsonJ M Jones
Apr 2, 1999·Science·M F PittengerD R Marshak
Dec 10, 1999·Proceedings of the National Academy of Sciences of the United States of America·K A JacksonM A Goodell
Jun 2, 2000·Science·D L ClarkeJ Frisén
Jan 11, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·M MüllerW M Franz
Jun 6, 2002·Proceedings of the National Academy of Sciences of the United States of America·Lijun YangAmmon B Peck
Apr 16, 2003·Cell Transplantation·Lakshmi RambhatlaMelissa K Carpenter
Mar 10, 2004·Cell·Amy J Wagers, Irving L Weissman
Dec 8, 2004·Stem Cells·Hsun Teresa KuJonathan S Bromberg
Oct 26, 2005·Molecular Therapy : the Journal of the American Society of Gene Therapy·Shin Yong MoonDong-Wook Kim
Nov 22, 2007·Science·Junying YuJames A Thomson
Dec 7, 2007·Nature Biotechnology·Masato NakagawaShinya Yamanaka
Jul 16, 2008·Circulation·Christina MauritzUlrich Martin
Dec 17, 2008·Cell Biology International·Shengwen Calvin LiWilliam Gunter Loudon
Jun 15, 2010·Journal of Conservative Dentistry : JCD·Roopa R Nadig
Dec 22, 2011·Archives of Toxicology·Jan G HengstlerMarcel Leist

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Citations

Jun 25, 2016·International Journal of Molecular Sciences·Shan LiuYuanyuan Zhang

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