Stem cells and genetic disease

Cell Proliferation
A Mackay-Sim, P Silburn

Abstract

Stem cell research is now a very broad field encompassing cells derived from all stages of life from the embryonic stem cells of the early blastocyst through to the adult stem cells of many tissues of the body. Adult stem cells from a variety of tissues are proving to be pluripotent and can differentiate into cell types different from the tissues from which they derive. Pre-clinical animal models indicate that adult stem cells do not cause tumours, not even, teratomas when transplanted. These properties, combined with the possibility of autologous transplantation, indicate significant advantages over embryonic stem cells in many proposed clinical applications.

References

Jan 1, 1981·Epidemiologic Reviews·M A Brinton, N Nathanson
Apr 26, 1996·Neuroreport·W MurrellA Mackay-Sim
Aug 26, 1998·Archives of Otolaryngology--head & Neck Surgery·F FéronA Mackay-Sim
Apr 28, 2000·Science·M Cavazzana-CalvoA Fischer
Jun 28, 2000·Progress in Neurobiology·A Mackay-Sima, M I Chuahb
Mar 10, 2001·Molecular Reproduction and Development·T Wakayama, R Yanagimachi
Nov 2, 2001·Nature·P Bianco, P G Robey
Jun 6, 2002·Journal of Cellular Biochemistry. Supplement·Christopher B BallasStanton L Gerson
Feb 3, 2004·The Journal of Comparative Neurology·Xueyan ChenJames E Schwob
Oct 28, 2004·Seminars in Hematology·Alain FischerMarina Cavazzana-Calvo
Mar 23, 2005·Nature Methods·Magdaline CostaEdouard G Stanley
Mar 23, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Wayne MurrellAlan Mackay-Sim
Apr 16, 2005·The Keio Journal of Medicine·Alan Mackay-Sim
Oct 13, 2005·Brain : a Journal of Neurology·F FéronA Mackay-Sim
Jun 30, 2006·Journal of Neurochemistry·Liat Benmoyal-Segal, Hermona Soreq
Jul 1, 2006·Nature·Claudio Bordignon
Aug 24, 2006·Expert Review of Anticancer Therapy·Jessica I Goldberg, Patrick I Borgen
Sep 14, 2006·Development·Hanna K A Mikkola, Stuart H Orkin
Sep 30, 2006·Reproductive Biomedicine Online·N FindikliS Kahraman
Oct 28, 2006·Annals of Neurology·John HardyAndrew Singleton
Nov 2, 2006·Current Medical Research and Opinion·Augusto Pessina, Laura Gribaldo

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Citations

Aug 12, 2010·Disease Models & Mechanisms·Nicholas MatigianAlan Mackay-Sim

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