Jun 20, 2015

Stem cells in Nanomia bijuga (Siphonophora), a colonial animal with localized growth zones

EvoDevo
Stefan SiebertCasey W Dunn

Abstract

Siphonophores (Hydrozoa) have unparalleled colony-level complexity, precision of colony organization, and functional specialization between zooids (i.e., the units that make up colonies). Previous work has shown that, unlike other colonial animals, most growth in siphonophores is restricted to one or two well-defined growth zones that are the sites of both elongation and zooid budding. It remained unknown, however, how this unique colony growth and development is realized at the cellular level. To understand the colony-level growth and development of siphonophores at the cellular level, we characterize the distribution of proliferating cells and interstitial stem cells (i-cells) in the siphonophore Nanomia bijuga. Within the colony, we find evidence that i-cells are present at the tip of the horn, the structure within the growth zone that gives rise to new zooids. Co-localized gene expression of vasa-1, pl10, piwi, nanos-1, and nanos-2 suggests that i-cells persist in the youngest zooid buds and that i-cells become progressively restricted to specific regions within the zooids until they are mostly absent from the oldest zooids. The examined genes remain expressed in gametogenic regions. No evidence for i-cells is found in the ...Continue Reading

  • References33
  • Citations6

References

  • References33
  • Citations6

Citations

Mentioned in this Paper

Gilia
Zone
Horns
PIWIL1 gene
Genes
Spatial Distribution
Interstitial
Bud - CHV Concept
Nanos
Gene Expression

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