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Stem cells, telomerase and dyskeratosis congenita

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology

Jan 23, 2003

Philip J Mason

Abstract

Dyskeratosis congenita is a rare skin and bone marrow failure syndrome caused by defective telomere maintenance in stem cells. The major X-linked form of the disease is due to mutations in a nucleolar protein, dyskerin, that is part of small nucleolar ribonucleoprotein particles that ar...read more

Mentioned in this Paper

Bone Marrow Failure Syndromes
Aplastic Anemia
Cell Cycle Proteins
Telomere Shortening
Telomerase Catalytic Subunit
Genetic Conditions, Dominant
Neoplasms
Tumor Lysis Syndrome
Ribosomal RNA
Etiology
Paper Details
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Stem cells, telomerase and dyskeratosis congenita

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology

Jan 23, 2003

Philip J Mason

PMID: 12539238

DOI: 10.1002/bies.10229

Abstract

Dyskeratosis congenita is a rare skin and bone marrow failure syndrome caused by defective telomere maintenance in stem cells. The major X-linked form of the disease is due to mutations in a nucleolar protein, dyskerin, that is part of small nucleolar ribonucleoprotein particles that ar...read more

Mentioned in this Paper

Bone Marrow Failure Syndromes
Aplastic Anemia
Cell Cycle Proteins
Telomere Shortening
Telomerase Catalytic Subunit
Genetic Conditions, Dominant
Neoplasms
Tumor Lysis Syndrome
Ribosomal RNA
Etiology
Paper Details
References
  • References
  • Citations42
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations42
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