Steno-occlusive arterial disease and early neurological deterioration in acute ischemic stroke

Cerebrovascular Diseases
Angel OisJaume Roquer

Abstract

To evaluate the influence that steno-occlusive arterial disease may have on the development of early neurological deterioration (END) in a large series of patients with acute ischemic stroke. We studied a prospective cohort of 1,093 patients admitted to a single tertiary hospital with presence of neurological symptoms in the first 24 h after stroke onset. END was defined as any increase in the National Institutes of Health Stroke Scale score >or=4 points in the first 72 h. The arterial study assessed the presence of arterial occlusion or significative stenosis in the symptomatic territory. Additionally, age, initial stroke severity, blood pressure, glucose levels, vascular risk factors, lacunar stroke and prior use of antithrombotic treatment were also analyzed in a multivariable analysis. END was detected in 179 patients (16.3%). Steno-occlusive disease (adjusted OR 3.60), initial blood pressure and abdominal obesity were independently associated with END. Both arterial stenosis (adjusted OR 2.33) or occlusions (adjusted OR 3.65) were associated with END. The higher adjusted OR (5.49) was obtained for steno-occlusive arterial disease in the vertebrobasilar system. An early arterial study may provide key data for the selection ...Continue Reading

References

Jul 1, 1989·Stroke; a Journal of Cerebral Circulation·E M ZanetteG L Lenzi
Jul 16, 1994·Lancet·H S JørgensenT S Olsen
Oct 1, 1994·Stroke; a Journal of Cerebral Circulation·M B RorickR J Adams
Nov 1, 1994·Stroke; a Journal of Cerebral Circulation·P LydenJ Marler
Apr 30, 1998·Archives of Neurology·H YamamotoG van Melle
Jan 8, 1999·Stroke; a Journal of Cerebral Circulation·R W BaumgartnerG Schroth
Nov 9, 2000·Cerebrovascular Diseases·C K KooK W Muir
Nov 22, 2000·Journal of Internal Medicine·A Rödén-Jüllig, M Britton
Mar 10, 2001·Stroke; a Journal of Cerebral Circulation·J C GrottaP D Lyden
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Apr 5, 2003·Stroke; a Journal of Cerebral Circulation·Harold P AdamsUNKNOWN Stroke Council of the American Stroke Association
May 31, 2003·Stroke; a Journal of Cerebral Circulation·Seung-Han SukUNKNOWN Northern Manhattan Stroke Study
Dec 4, 2003·Journal of Internal Medicine·A Rödén-JülligB Leijd
Jan 7, 2004·Journal of the Neurological Sciences·Noriko MatsumotoKazuo Minematsu
Jun 5, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Gunnar EngströmFolke Lindgärde
Nov 17, 2004·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Francisco José AlvarezJoaquín Serena
Mar 16, 2005·Archives of Neurology·Christian WeimarUNKNOWN German Stroke Study Collaboration
Apr 2, 2005·Stroke; a Journal of Cerebral Circulation·David TanneUri Goldbourt
Nov 12, 2005·Cerebrovascular Diseases·Vadim G KarepovNatan M Bornstein
Jan 25, 2006·Circulation·Scott E KasnerUNKNOWN Warfarin Aspirin Symptomatic Intracranial Disease Trial Investigators
May 3, 2006·Cerebrovascular Diseases·Joaquín SerenaMar Castellanos
Sep 22, 2006·Lancet Neurology·Jens AllendoerferUNKNOWN Neurosonology in Acute Ischemic Stroke Study Group

❮ Previous
Next ❯

Citations

Apr 24, 2013·Clinical Neurology and Neurosurgery·Dong-Eun KimKi-Hyun Cho
Apr 13, 2011·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J-T KimK-H Cho
Feb 25, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Jung-Gon LeeHye-Won Hwang
May 29, 2012·Revue neurologique·D PuginUNKNOWN French Society of Intensive Care
May 15, 2012·Journal of the Neurological Sciences·Kang-Ho ChoiKi-Hyun Cho
Jan 27, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Woo-Keun SeoKun-Woo Park
Sep 10, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Nobukazu MiyamotoTakao Urabe
Dec 15, 2010·Clinical Neurology and Neurosurgery·Jean-Marc BugnicourtOlivier Godefroy
Sep 5, 2014·International Journal of Stroke : Official Journal of the International Stroke Society·Zuowei DuanXinfeng Liu
Dec 31, 2009·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Joon-Tae KimKi-Hyun Cho
Jul 22, 2014·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·W SunX Liu
Mar 30, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Woo-Keun SeoHae Young Seol
Feb 24, 2017·Stroke; a Journal of Cerebral Circulation·Fana AlemsegedBruce C V Campbell
Apr 25, 2009·Stroke; a Journal of Cerebral Circulation·Josef A AlawnehJean-Claude Baron
Jun 20, 2017·Stroke; a Journal of Cerebral Circulation·Changqing ZhangUNKNOWN Chinese IntraCranial AtheroSclerosis (CICAS) Study Group
Jun 6, 2009·Stroke; a Journal of Cerebral Circulation·Angel OisJaume Roquer
Feb 20, 2019·International Journal of Stroke : Official Journal of the International Stroke Society·Ying ZhouMin Lou
Jan 16, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Donghua MiLiping Liu
Aug 14, 2020·Journal of Neurology·Carol Soriano-TárragaJaume Roquer
Aug 9, 2020·International Journal of Hypertension·Xinsheng HanLi Chen
Jan 3, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Xiaohua XieLijie Ren

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.