Steppingstone and gateway ideas: a discussion of origins, research challenges, and promising lines of research for the future.

Drug and Alcohol Dependence
James C Anthony

Abstract

In this discussion of contributed papers for the special issue of DAD, the author draws attention to early American laws concerning cannabis and to statements made about the epidemiology of cannabis smoking and other drug use between 1858 and the contemporary scene, with coverage of opium, heroin, tobacco, alcohol, cocaine, kava, and other drugs. He discusses these steppingstone and gateway processes in relation to political environment and in relation to scientific challenges such as uncontrolled confounding. He provides a critique of between-individual research designs, including co-twin and co-sib designs of behavior genetics, as well as imaging research, where uncontrolled confounding often exists. He highlights the epidemiologic case-crossover design and prevention research experiments as potentially valuable approaches in new directions for research on the steppingstone and gateway processes.

References

Jun 10, 2000·Substance Use & Misuse·L T Wu, J C Anthony
Mar 22, 2002·Drug and Alcohol Dependence·Holly C WilcoxJames C Anthony
Jan 17, 2004·Drug and Alcohol Dependence·C Debra M Furr-HoldenSheppard G Kellam
Jun 12, 2004·American Journal of Epidemiology·Chuan-Yu ChenJames C Anthony
Aug 9, 2008·American Journal of Epidemiology·Valerie S HarderJames C Anthony
Feb 4, 2011·Drug and Alcohol Dependence·Carla L StorrJames C Anthony
Jan 10, 2012·International Journal of Methods in Psychiatric Research·Megan S O'BrienJames C Anthony

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Citations

Feb 18, 2016·Substance Use & Misuse·Susan ChaBriana Mezuk
Jan 16, 2014·Addiction·David M Fergusson, Joseph M Boden
Jan 21, 2014·Addiction·Arpana Agrawal, Michael T Lynskey
Feb 5, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Benzi KlugerJoseph Jankovic
Apr 8, 2016·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Tord Finne Vedøy
Oct 4, 2013·Substance Use & Misuse·My Lilja
Aug 26, 2014·Social Science & Medicine·Kirsten Bell, Helen Keane
Sep 14, 2016·Annual Review of Pharmacology and Toxicology·Nora D VolkowRuben D Baler
Jan 23, 2018·Translational Psychiatry·Maria Carla GerraClaudia Donnini
Mar 25, 2017·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Brian J Fairman, James C Anthony
Oct 24, 2017·Current Addiction Reports·Kelly E CourtneyJoanna Jacobus

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