Stereo- and regio-selective one-pot synthesis of triazole-based unnatural amino acids and β-amino triazoles

Chemical Communications : Chem Comm
R B Nasir Baig, Rajender S Varma

Abstract

Synthesis of triazole based unnatural amino acids and β-amino triazoles has been described via a stereo and regioselective one-pot multi-component reaction of sulfamidates, sodium azide, and alkynes under MW conditions. The developed method is applicable to a broad substrate scope and has significant potential for the synthesis of unnatural amino acids with a triazole side chain.

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Citations

Mar 29, 2014·Accounts of Chemical Research·Manoj B GawandeRajender S Varma
Dec 6, 2012·Chemical Communications : Chem Comm·R B Nasir Baig, Rajender S Varma
Jun 4, 2014·Chemical Reviews·Dong Wang, Didier Astruc
Aug 1, 2018·Chemistry, an Asian Journal·Yogesh G ShelkeAnant R Kapdi
May 18, 2012·Chemical Communications : Chem Comm·R B Nasir Baig, Rajender S Varma
Jul 21, 2012·Chemical Communications : Chem Comm·Amit SahaRajender S Varma
Nov 18, 2017·The Journal of Organic Chemistry·Claudio D NavoGonzalo Jiménez-Osés

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