Stereo- and regioselective photocycloaddition of extended alkenes using γ-cyclodextrin

Organic & Biomolecular Chemistry
Akshay KashyapMahesh Pattabiraman

Abstract

Photoexcitation of dibenzalacetones (1a-d) in homogeneous media and solid state yields a mixture of products with poor conversions. Irradiation of the reactants complexed to γ-cyclodextrin predominantly affords a single dimer (syn adduct 6) despite the possibility for several monomeric and dimeric products. High selectivity in the cavitand-mediated reaction along with the structural characterization of the inclusion complex provides insight into the supramolecular interactions that drive the self-assembly of the host-guest system.

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Methods Mentioned

BETA
PCA
NMR
X-ray

Software Mentioned

NanoAnalyze®

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