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Stereoselective formation of bis(alpha-aminoacyl) esters of 5'-AMP suggests a primitive peptide synthesizing system with a preference for L-amino acids

Biochimica Et Biophysica Acta

Feb 15, 1991

Jeffrey C LaceyClaire L Watkins

PMID: 2001387

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Abstract

In the biosynthesis of proteins, each amino acid passes from the aminoacyl adenylate to become an amino acid ester and finally a 2' (3') peptidyl ester of the AMP residue at the end of a tRNA. Consequently, the chemistry of protein synthesis is the chemistry of aminoacyl and peptidyl AM...read more

Mentioned in this Paper

Amino Acid [EPC]
Protein Biosynthesis
N-acetylphenylalanine, (L)-isomer,3H-labeled
Triplet Codon-amino Acid Adaptor Activity
Isomerism
Transfer RNA
Polypeptides
One-Step Dentin Bonding System
In Vivo NMR Spectroscopy
Anabolism
Paper Details
References
  • References4
  • Citations7
1

Stereoselective formation of bis(alpha-aminoacyl) esters of 5'-AMP suggests a primitive peptide synthesizing system with a preference for L-amino acids

Biochimica Et Biophysica Acta

Feb 15, 1991

Jeffrey C LaceyClaire L Watkins

PMID: 2001387

DOI:

Abstract

In the biosynthesis of proteins, each amino acid passes from the aminoacyl adenylate to become an amino acid ester and finally a 2' (3') peptidyl ester of the AMP residue at the end of a tRNA. Consequently, the chemistry of protein synthesis is the chemistry of aminoacyl and peptidyl AM...read more

Mentioned in this Paper

Amino Acid [EPC]
Protein Biosynthesis
N-acetylphenylalanine, (L)-isomer,3H-labeled
Triplet Codon-amino Acid Adaptor Activity
Isomerism

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Paper Details
References
  • References4
  • Citations7
1

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