Stereotactic Radiosurgery for High-Grade Intracranial Dural Arteriovenous Fistulas

World Neurosurgery
Ching-Jen ChenJason P Sheehan

Abstract

Factors associated with favorable outcome after stereotactic radiosurgery (SRS) for dural arteriovenous fistulas (DAVFs) with cortical venous reflux (CVR) are not completely understood. The aim of this retrospective cohort study was to assess the outcomes after SRS for high-grade DAVFs and identify predictors. We performed a retrospective review of consecutive patients with high-grade DAVFs, defined as the presence of CVR, who underwent SRS between 1989 and 2017. The primary outcome was defined as DAVF obliteration without a new permanent neurologic deficit. Predictors of outcomes were determined using multivariate logistic regression. The study cohort was composed of 41 high-grade DAVF patients with a mean age of 52 years. DAVF obliteration without a new permanent neurologic deficit was achieved in 62% of patients (13/21). The rates of complete obliteration and new permanent neurologic deficit were 63% (17/27) and 23% (7/30) of patients, respectively. No independent predictors of the primary outcome or angiographic obliteration were identified in the multivariate model. Presentation with a nonhemorrhagic neurologic deficit (NHND) was found to be an independent predictor of a new permanent neurologic deficit after SRS (odds rat...Continue Reading

References

May 4, 2002·Stroke; a Journal of Cerebral Circulation·J Marc C van DijkM Christopher Wallace
Apr 5, 2008·Stroke; a Journal of Cerebral Circulation·Michael SödermanTommy Andersson
Sep 28, 2010·Neurosurgery·Christopher P CifarelliJason P Sheehan
May 23, 2012·Neurosurgery·Bradley A Gross, Rose Du
Dec 5, 2012·Journal of Cerebrovascular and Endovascular Neurosurgery·Jung Tae OhHan Kyu Kim
Dec 28, 2012·Neurologia Medico-chirurgica·Shunya HanakitaNobuhito Saito

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Citations

Feb 15, 2021·Neurosurgery·Ching-Jen ChenUNKNOWN Consortium for Dural Arteriovenous Fistula Outcomes Research
Mar 1, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Benton MaglingerJustin F Fraser

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