Stereotactic radiosurgery for postgeniculate visual pathway arteriovenous malformations

Journal of Neurosurgery
B E PollockJ C Flickinger

Abstract

Arteriovenous malformations (AVMs) that are located within the postgeniculate optic radiations or striate cortex are difficult to resect without creating postoperative visual defects. To reduce the risk of an AVM hemorrhage and to enhance the possibility of preserving visual function, the authors performed stereotactic radiosurgery in 34 patients with newly diagnosed or residual AVMs of the visual pathways. The mean AVM volume was 4.7 ml, and the average radiation dose to the AVM margin was 21 Gy. The median follow up was 47 months (range 16-83 months). Two (6%) of 34 patients had documented new visual field defects (central scotoma in one, and partial hemianopsia in one) after single-stage radiosurgery, but no patient developed a new permanent homonymous hemianopsia. Angiography was performed in all patients at a median of 26 months after radiosurgery: 22 (65%) had complete obliteration, 10 (29%) had a significant decrease in AVM volume, one (3%) had only a persistent early draining vein without residual nidus, and one (3%) had no change in the AVM. Thirteen (81%) of 16 patients with AVMs less of than 4 ml had complete obliteration. Five patients had second-stage stereotactic radiosurgery after angiography revealed a persisten...Continue Reading

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Citations

Feb 3, 2007·Pituitary·Brian K RobertsLaurence Katznelson
Jun 11, 1999·The New England Journal of Medicine·UNKNOWN Arteriovenous Malformation Study Group
Oct 17, 2007·Journal of Neurosurgery·Keisuke MaruyamaNobuhito Saito
Jul 25, 2012·Surgical Neurology International·Andres R Plasencia, Alejandro Santillan
Dec 2, 2010·Acta neurochirurgica·Azize BoströmJohannes Schramm
Oct 16, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Jason A EllisRobert A Solomon
Feb 13, 1999·Mayo Clinic Proceedings·B E PollockR W Kline
Feb 25, 2011·International Journal of Radiation Oncology, Biology, Physics·Caroline HayhurstGelareh Zadeh
Nov 26, 2014·Journal of Neurosurgery·Greg BowdenL Dade Lunsford
Nov 7, 2009·Journal of Korean Neurosurgical Society·Sung Ho LeeBong Arm Rhee
Jul 9, 2009·International Ophthalmology Clinics·Prem S Subramanian, Zoë R Williams
Aug 18, 1999·Arquivos de neuro-psiquiatria·C M GuiotokuM S Meneses

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Methods Mentioned

BETA
surgical resection
PCA

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