PMID: 11316556Apr 24, 2001Paper

Stereotactic radiosurgery in the management of angiographically occult vascular malformations

International Journal of Radiation Oncology, Biology, Physics
C TsienE Podgorsak

Abstract

To evaluate the role of stereotactic radiosurgery in the treatment of angiographically occult vascular malformations (AOVMs). From 1987 to 1996, 21 patients, 10 males and 11 females, median age of 41 years (range: 7-75 years), with an intracerebral AOVM underwent stereotactic radiosurgery at our institution. All were considered at high risk for surgical intervention. The vascular lesions were located in the brainstem (17 patients), basal ganglia (2), occipital lobe (1), and cerebellum (1). Diagnosis was based on high-resolution magnetic resonance imaging (MRI). Clinical presentation at onset included previous intracerebral hemorrhage (20 patients) and epilepsy (1). All patients were treated with a linac-based radiosurgical technique. The median dose delivered was 25 Gy (range 13-50 Gy), typically prescribed to the 80-90% isodose surface (range 50-90%), which corresponded to the periphery of the vascular malformation. Patients were followed by clinical neurologic assessment and by MRI on a regular interval basis. Follow-up was obtained in 20 patients; clinical or MRI information was not available for 1 patient, and this patient was excluded from our analysis. At a median follow-up of 77 months (range: 4-141 months), follow-up MR...Continue Reading

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Citations

Feb 9, 2012·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·M FuetschM Maarouf
Nov 19, 2015·World Neurosurgery·Joseph M ZabramskiRobert F Spetzler
Mar 19, 2014·World Neurosurgery·Kaith K Almefty, Robert F Spetzler
May 17, 2006·Clinical Neurology and Neurosurgery·Yin-Cheng HuangPeng-Wei Hsu
Mar 29, 2014·Journal of Neurology, Neurosurgery, and Psychiatry·Michiel H F PoorthuisRustam Al-Shahi Salman
Feb 23, 2010·Journal of Neurosurgery·Ladislau SteinerDavid Schlesinger
May 5, 2009·Neurosurgical Focus·Martin PhamH Hunt Batjer
Oct 30, 2019·Neurology·Michiel H F PoorthuisRustam Al-Shahi Salman

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