Stereotactic Radiotherapy for the Management of Refractory Ventricular Tachycardia: Promise and Future Directions

Frontiers in Cardiovascular Medicine
Raphaël JumeauÉtienne Pruvot

Abstract

Ventricular tachycardia (VT) caused by myocardial scaring bears a significant risk of mortality and morbidity. Antiarrhythmic drug therapy (AAD) and catheter ablation remain the cornerstone of VT management, but both treatments have limited efficacy and potential adverse effects. Stereotactic body radiotherapy (SBRT) is routinely used in oncology to treat non-invasively solid tumors with high precision and efficacy. Recently, this technology has been evaluated for the treatment of VT. This review presents the basic underlying principles, proof of concept, and main results of trials and case series that used SBRT for the treatment of VT refractory to AAD and catheter ablation.

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Citations

Nov 8, 2020·International Journal of Radiation Oncology, Biology, Physics·Suzanne Lydiard PGDipPaul Keall
Jul 8, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Boldizsar KovacsArdan M Saguner

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Methods Mentioned

BETA
X-ray
irradiate
irradiating
imaging technique

Clinical Trials Mentioned

NCT02919618
NCT03819504
NCT03867747
NCT04066517
NCT04065802

Software Mentioned

RAVENTA
ENCORE
VT

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