Sterilization of ginseng using a high pressure CO2 at moderate temperatures

Biotechnology and Bioengineering
Fariba DehghaniAldric Tumilar

Abstract

The aim of this study was to determine the feasibility of using high pressure CO2 for sterilization of Ginseng powder, as an alternative method to conventional techniques such as gamma-irradiation and ethylene oxide. The Ginseng sample used in this study was originally contaminated with fungi and 5 x 10(7) bacteria/g that was not suitable for oral use. This is the first time that high pressure CO2 has been used for the sterilization of herbal medicine to decrease the total aerobic microbial count (TAMC) and fungi. The effect of the process duration, operating pressure, temperature, and amount of additives on the sterilization efficiency of high pressure CO2 were investigated. The process duration was varied over 15 h; the pressure between 100 and 200 bar and the temperature between 25 and 75 degrees C. A 2.67-log reduction of bacteria in the Ginseng sample was achieved after long treatment time of 15 h at 60 degrees C and 100 bar, when using neat carbon dioxide. However, the addition of a small quantity of water/ethanol/H2O2 mixture, as low as 0.02 mL of each additive/g Ginseng powder, was sufficient for complete inactivation of fungi within 6 h at 60 degrees C and 100 bar. At these conditions the bacterial count was decreased ...Continue Reading

References

Jul 31, 1998·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·J FagesR Guidoin
Jan 30, 1999·Applied and Environmental Microbiology·E Debs-LoukaK Allaf
Sep 1, 1999·Proceedings of the National Academy of Sciences of the United States of America·A K DillowR Langer
Feb 24, 2001·International Journal of Food Microbiology·S I Hon, Y R Pyun
Feb 19, 2002·Journal of Applied Microbiology·B SetlowP Setlow
Dec 25, 2002·Journal of Ethnopharmacology·Kazunori HashimotoHiroshi Sasaki
Feb 6, 2003·Biotechnology and Bioengineering·Sara SpilimbergoNeil R Foster
Aug 28, 2003·Integrative Cancer Therapies·Yuan S ChangKeith I Block
Apr 9, 2005·Clinical and Diagnostic Laboratory Immunology·Heungsup SungYoung-Keol Cho
Jul 19, 2005·Biotechnology and Bioengineering·Sara SpilimbergoGiulio Bertoloni
Oct 20, 2005·Journal of Bioscience and Bioengineering·N YoshidaK Ogawa
Jan 26, 2006·International Journal of Food Microbiology·V H TournasE J Miracco
Feb 25, 2006·Journal of Biotechnology·Angela WhiteTim W Christensen
Mar 7, 2006·Journal of Microbiological Methods·Jian ZhangYuehuei H An
Jul 14, 2006·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jason D HemmerMichael A Matthews
Sep 5, 2006·Evidence-based Complementary and Alternative Medicine : ECAM·John Zeqi Luo, Luguang Luo
Oct 1, 2007·The Journal of Supercritical Fluids·A JiménezA Trapotsis

❮ Previous
Next ❯

Citations

Feb 22, 2011·Biotechnology and Bioengineering·Sandeep S KarajanagiNeil R Foster
Jul 30, 2021·Comprehensive Reviews in Food Science and Food Safety·Surabhi WasonJeyamkondan Subbiah

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
A K DillowR Langer
Biotechnology and Bioengineering
Sara Spilimbergo, A Bertucco
© 2022 Meta ULC. All rights reserved