Steroid therapy in an infant with human herpesvirus 6 encephalopathy

Brain & Development
Hideo EnokiTadashi Matsubayashi

Abstract

We describe a 10-month-old girl who developed convulsive status during febrile illness. Human herpesvirus 6 DNA was detected in both the serum and the cerebrospinal fluid by polymerase chain reaction. Interleukin-6 was increased in the serum. The patient improved after a commencement of steroids pulse therapy. This case suggests that proinflammatory cytokines are responsible for the pathogenesis of the encephalopathy.

References

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Oct 11, 2002·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Tohshin Go, Kenji Nakamura

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