Steroids from the roots of Asparagus officinalis and their cytotoxic activity

Journal of Integrative Plant Biology
Xuefeng HuangLingyi Kong

Abstract

One new (Sarsasapogenin O) and seven known steroids were isolated from the roots of Asparagus officinalis L. Their structures were elucidated on the basis of spectroscopic analysis, including various 2D-NMR techniques, hydrolysis, and by comparison of spectral data of known compounds. These compounds together with nine steroids which were previously isolated from this plant, were tested for cytotoxic activity. Among them, eight compounds displayed significant cytotoxicities against human A2780, HO-8910, Eca-109, MGC-803, CNE, LTEP-a-2, KB and mouse L1210 tumor cells.

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Nov 11, 2005·Steroids·Xuefeng Huang, Lingyi Kong

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Citations

Jun 26, 2013·Journal of Asian Natural Products Research·Qing-Bo LiuShao-Jiang Song
Jul 1, 2010·Pharmacognosy Reviews·J S NegiV K Bisht
Mar 4, 2009·Biochemical and Biophysical Research Communications·Wei LiuQing-Long Guo
Sep 17, 2014·Journal of Asian Natural Products Research·Jian-Chao YuanBai-Ping Ma
Sep 14, 2016·Journal of Asian Natural Products Research·Xue-Mei LiZi-Chao Mao
Apr 17, 2017·Chinese Journal of Natural Medicines·Xing-Huan SunXue-Feng Huang
Sep 14, 2010·Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe·Irma PodolakDanuta Sobolewska
Feb 6, 2020·Chemistry & Biodiversity·Beatriz Pereira MorenoDebora Cristina Baldoqui
Oct 10, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lu QuTao Wang
Oct 7, 2020·Journal of Ethnopharmacology·Ilyass Alami Merrouni, Mostafa Elachouri
Sep 3, 2020·Fitoterapia·Vaderament-A Nchiozem-NgnitedemMichael Spiteller
Aug 17, 2021·Nutrition and Cancer·Deepa S Mandlik, Satish K Mandlik
Nov 10, 2012·Journal of Agricultural and Food Chemistry·Corinna Dawid, Thomas Hofmann

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