Sterols of scallop. I. Application of hydrophobic sephadex derivatives to the resolution of a complex mixture of marine sterols

Journal of Chromatography
G W PattersonD R Idler

Abstract

Column chromatography on a hydroxyalkoxypropyl derivative of Sephadex LH-20 and on Anasil B has been applied to the resolution of complex marine sterol mixture in combination with argentation thin-layer chromatography and gas chromatography. This approach permits isolation in quantity of individual sterols from a complex mixture and separation of sterol mixtures that were not resolved without the modified Sephadex step. Seventeen sterols were detected in the scallop Placopecten magellanicus. 24-Methyl-cholesterol, 24-ethyl-cholesterol, 24-methyl-22-dehydrocholesterol and 24-ethyl-22-dehydrocholesterol, i.e. sterols whose configuration at C-24 had not been definitively established, were isolated in sufficient quantities for further study by nuclear magnetic resonance spectroscopy.

References

Aug 1, 1974·Lipids·L J GoadT W Goodwin
Apr 26, 1972·Journal of Chromatography·P M Hyde, W H Elliott
Mar 1, 1972·Steroids·D R Idler, L M Safe

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Citations

Jan 1, 1976·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·M W Khalil, D R Idler
Mar 12, 2003·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·A J PazosM Abad
May 15, 1977·Analytical Biochemistry·B A Knights

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