PMID: 2491550Jun 1, 1989Paper

Still's disease of the adult: analysis of a series of 9 cases

Anales de medicina interna : organo oficial de la Sociedad Española de Medicina Interna
R Cervera SeguraA Urbano-Márquez

Abstract

Characteristic features of 9 patients (5 male, 4 female) affected by Still's disease of adult (SDA) were analysed. All of them had fever and in 7 cases it was associated to arthritis and cutaneous rash. The most frequently affected joints were knees, ankles, and carpus. The sedimentation rate was increased in all patients and 6 of them had associated leucocytosis. 5 patients had mild inflammation synovial fluid. The histological changes found were: cutaneous perivascular inflammation, reactive lymph node enlargement, sinusoid dilatation and hepatic periportal inflammation. The NSA were active in 4 patients but 5 needed steroids to control the systemic clinical alterations. 3 patients relapsed and one was diagnosed as having sarcoidosis 3 years later, the possible association not having being described. We concluded that suspicion is the most important factor for an early diagnosis.

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