Stimulant methamphetamine and dextromethorphan use among Thai adolescents: implications for health of women and children.

Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology
Chulathida Chomchai, Boonying Manaboriboon

Abstract

For over a decade, amphetamine-type stimulants have made their way into the adolescent culture of Thailand. Coupled with the more recent emergence of the legal, over-the-counter cough medicine dextromethorphan (DM), they represent the most commonly abused substances among Thai youths today. Methamphetamine is the second most popular drug of abuse in Thailand, the first being cannabis. It is available in the crystalline version, ICE, and the less pure methamphetamine tablets. The tablets are frequently crushed and smoked. Its use has gained enormous popularity among teenagers and young adults, including women of child-bearing age. As such, it has become the most common drug being detected in the urine of peripartum women, resulting in peripartum and postpartum complications for both mother and child. DM is a newer drug which has gained popularity among middle school and high school students due to its easy availability as a single product over the counter. It is usually taken with soft drinks at parties and gathering. It is metabolized by CYP4502D6 to dextrorphan, the substance responsible for the feeling of euphoria. Consequently, those who are poor metabolizers often experience the "negative" effects associated with the drug. ...Continue Reading

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Citations

Jul 17, 2012·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·D M Wood, P I Dargan
Aug 13, 2015·Journal of Psychoactive Drugs·George PringleKara I Gabriel
Aug 2, 2015·Progress in Neuro-psychopharmacology & Biological Psychiatry·Colin Davidson, Fabrizio Schifano
May 24, 2015·Current Opinion in Psychiatry·Chulathida Chomchai, Summon Chomchai
Mar 24, 2010·Journal of Psychosomatic Research·Sean Hatherill, Alan J Flisher
Oct 11, 2015·Journal of Human Lactation : Official Journal of International Lactation Consultant Association·Chulathida ChomchaiRatchada Kitsommart
Mar 1, 2018·Drug and Alcohol Review·Chaisiri AngkurawaranonApinun Aramrattana
Jan 11, 2014·Current Opinion in HIV and AIDS·Nabila El-BasselSteffanie A Strathdee

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