Stimulating adverse drug reaction reporting: effect of a drug safety bulletin and of including yellow cards in prescription pads

Drug Safety : an International Journal of Medical Toxicology and Drug Experience
Josep Maria CastelDolors Capellà

Abstract

The effectiveness of voluntary reporting systems in pharmacovigilance highly depends on the number of assembled reports. The aim of this study was to measure the effect of the periodical distribution of a bulletin on drug safety issues and of including yellow cards in prescription pads on the rate of adverse drug reaction (ADR) reporting. The Catalan Centre of Pharmacovigilance began its activities at the end of 1982. Since 1985, an ADR bulletin (ADRB) has been mailed approximately quarterly to all physicians in its catchment area, with one yellow card enclosed. Additionally, from 1991-1994, a yellow card was included in the prescription pads of the Catalan Health Service. Time series methodology, with adjustment of the monthly number of reports to an Auto-Regressive Integrated Moving Average (ARIMA) model, was used to evaluate the effect of these two measures. From January 1983-October 1995, 6240 spontaneous ADR reports were received, and 41 issues of the ADRB were sent out. Initially, the mean monthly spontaneous ADR reporting rate was 34.4 (SD = 14.1; n = 106 months). After the inclusion of yellow cards in prescription pads, the mean monthly spontaneous ADR reporting rate increased to 53.9 (SD = 14.4; n = 48 months). Accordi...Continue Reading

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Citations

May 3, 2007·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Jimmy JoseBeena Jimmy
Jan 10, 2009·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Consuelo PedrósJosep M Arnau
Dec 6, 2012·Pharmacoepidemiology and Drug Safety·Christelle CholPatrick Mismetti
May 4, 2013·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Cristian Gonzalez-GonzalezAdolfo Figueiras
Feb 23, 2018·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Ed WhalenAndrew Bate
May 21, 2020·Pharmacoepidemiology and Drug Safety·Malahat KhaliliAli Akbar Haghdoost
Aug 27, 2005·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Maria T HerdeiroJuan Jesus Gestal-Otero
Jan 8, 2009·European Journal of Clinical Pharmacology·Marie-Louise JohanssonSusanna M Wallerstedt
Mar 10, 2007·European Journal of Clinical Pharmacology·Susanna M WallerstedtLars Ny
Jun 19, 2012·European Journal of Clinical Pharmacology·Chiara BiagiDomenico Motola
Jul 14, 2012·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Maria T HerdeiroAdolfo Figueiras
Mar 18, 2020·Pharmacoepidemiology and Drug Safety·Thamir M AlshammariSondus I Ata
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Apr 20, 2010·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Mireille GonyHaleh Bagheri
Oct 22, 2020·Pharmacoepidemiology and Drug Safety·Rema PanickarZoriah Aziz

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