PMID: 6402794Jan 1, 1983Paper

Stimulation of arachidonic acid metabolism in rat kidney mesangial cells by bradykinin, antidiuretic hormone, and their analogues

Prostaglandins, Leukotrienes, and Medicine
A UglesityL Levine

Abstract

Kinins, antidiuretic hormone, and several of their analogues stimulated contractile rat kidney mesangial cells growing in culture to produce prostaglandins E2, F2 alpha, and I2. Analogues that are known to be pharmacologically active stimulated arachidonic acid metabolism in these cells, whereas compounds that have little activity were ineffective. Stimulation of arachidonic acid metabolism by these agonists appeared to be receptor-mediated. It is possible that arachidonic acid metabolism is stimulated by contraction of mesangial cells and the released prostaglandins regulate glomerular function.

References

Jul 1, 1978·Kidney International·J I KreisbergM J Karnovsky
Jan 1, 1978·Contributions to Nephrology·J C McGiffN A Terragno
Aug 1, 1975·Clinical Science and Molecular Medicine·J C McGiffN A Terragno
Apr 1, 1976·The American Journal of Physiology·C BaylisB M Brenner
Jul 1, 1972·Circulation Research·J C McGiffA J Lonigro

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Citations

Nov 13, 1990·European Journal of Pharmacology·C EmondJ P Girolami
Dec 27, 1995·European Journal of Pharmacology·F PraddaudeJ L Ader
Sep 1, 1986·Molecular and Cellular Endocrinology·J B Foidart, P Mahieu
Mar 1, 1991·British Journal of Pharmacology·F J HockJ Knolle
Jan 1, 1986·Kidney International·D Schlondorff, R Ardaillou
Jan 1, 1986·Kidney International·A G Scicli, O A Carretero
Feb 1, 1985·Immunological Investigations·K J LavelleM N Yum

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