PMID: 2095576Nov 1, 1990Paper

Stimulation of cultured iridophores by amphibian ventral conditioned medium

Pigment Cell Research
J T Bagnara, T Fukuzawa

Abstract

That the ventral integument of adult frogs (Rana pipiens) contains factor(s) that stimulate iridophore expression (adhesion, morphologic appearance, proliferation) was demonstrated on iridophores derived from tadpoles of R. pipiens and Pachymedusa dacnicolor, and maintained in primary culture in a growth medium based upon Leibovitz's L-15. Experimental growth medium (VCM) conditioned by a one-hour exposure to pieces of ventral skin of adult R. pipiens induced iridophores to assume a broad and stellate appearance, to form confluent sheets, and to proliferate over a nine-day period. Iridophores in control medium assumed long thin profiles, detached easily, and exhibited no signs of proliferation. Unknown cells containing reflecting platelets and unusual other organelles appeared uniquely in chromatophore cultures of P. dacnicolor in VCM. The intense stimulation of iridophore expression in VCM is consistent with the known inhibitory effect of this medium on melanization and with its purported role in the determination of dorsal/ventral pigment patterns of amphibians. The results are discussed in terms of a prevailing theory about pigment cell origins and development.

References

Feb 2, 1979·Science·J T BagnaraJ D Taylor
Jan 1, 1988·Pigment Cell Research·J T BagnaraA C Cohen
Sep 1, 1988·Developmental Biology·T Fukuzawa, H Ide
Sep 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·V TwittyO Anderson
Jul 1, 1968·The Journal of Cell Biology·J T BagnaraM E Hadley
Mar 1, 1958·The Journal of Experimental Zoology·J T BAGNARA

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Citations

Nov 1, 1992·Pigment Cell Research·T FukuzawaJ T Bagnara
Nov 1, 1992·Pigment Cell Research·A ZuastiJ T Bagnara
Apr 1, 1993·Journal of Morphology·P J Fernandez, J T Bagnara
Aug 1, 1992·The Journal of Experimental Zoology·F T ManganoJ T Bagnara
Apr 8, 1999·Pigment Cell Research·J T Bagnara
Jan 7, 2011·European Journal of Pharmacology·José Miguel Cerdá-ReverterJosep Rotllant
Dec 17, 2008·Seminars in Cell & Developmental Biology·Margaret G Mills, Larissa B Patterson
Dec 4, 2014·Pigment Cell & Melanoma Research·Rosa M CeinosJosep Rotllant
Feb 6, 2013·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Aude AndoucheLaure Bonnaud

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