PMID: 321232Mar 1, 1977

Stimulation of erythropoiesis in a grafted animal by mouse fetal liver culture media

Experimental Hematology
J R ZucaliE A Mirand


Erythropoietin given to polycythemic, irradiated mice receiving a bone marrow transplant restores the number of erythroid colonies produced. In this study mouse fetal liver culture media administered to polycythemic, irradiated mice also restored the number of erythroid colonies and erythropoiesis as measured by 59Fe incorporation. Thus, mouse fetal liver in culture produces a factor which resembles erythropoietin.

Related Concepts

Effects of Radiation
Cell Division Phases
Transplantation, Homologous
Bone Marrow Cell Transplantation
Bone Marrow Cells
Clone Cells

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