PMID: 697502Jul 1, 1978Paper

Stimulation of growth and glucose catabolite enzymes by succinate in some thermophilic fungi

Archives of Microbiology
A S WaliV V Modi

Abstract

Thermophilic Humicola lanuginosa, Penicillium duponti, Sporotrichum thermophile and Mucor pusillus required succinate in addition to glucose for optimal growth. The requirement for succinate was concentration-dependent and the concentration needed for one half of the maximal growth was 6.14mM. In the presence of succinate, glucose utilization from the medium was markedly increased and this was associated with increased levels of the enzymes of the glycolytic and Krebs cycle pathways. Addition of succinate to cultures growing in glucose at any stage of growth stimulated the growth with the resulting rate of growth remaining high if the addition was made within 3 days of inoculation. Cycloheximide (71.4 micrometer) prevented the succinate-mediated derepression of the enzymes suggesting that succinate may remove the catabolite repression in the presence of glucose.

References

Aug 1, 1976·Journal of General Microbiology·S L Levinson, T A Krulwich
Oct 23, 1974·Biochemical and Biophysical Research Communications·A K Mattoo, J R Rao
Feb 1, 1973·Journal of Bacteriology·M E Sobel, T A Krulwich
Sep 1, 1974·Canadian Journal of Biochemistry·V BoonsaengM G Shepherd
Nov 1, 1974·The Biochemical Journal·H M MillerM G Shepherd
Jun 1, 1961·Canadian Journal of Microbiology·B D SANWAL, M LATA

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Citations

Sep 7, 2000·Microbiology and Molecular Biology Reviews : MMBR·R MaheshwariM K Bhat
Jan 19, 2016·Critical Reviews in Microbiology·Bijender SinghTulasi Satyanarayana
Aug 1, 1979·International Journal of Peptide and Protein Research·A S WaliV V Modi
Jan 1, 1983·Zeitschrift für allgemeine Mikrobiologie·H Weide
Nov 1, 1983·Journal of Bacteriology·C WrightE W Somberg

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