PMID: 3697715Mar 5, 1986

Stimulation of tryptophan uptake into brain microvessels by D-glutamine

Brain Research
M Gorgievski-HrisohoC Bachmann

Abstract

The uptake of L-tryptophan into isolated porcine microvessels is increased by preincubation with L-glutamine as well as with D-glutamine. This could indicate that gamma-glutamyltranspeptidase is involved in the stimulation of uptake of large neutral amino acids into the brain observed in hyperammonemic conditions.

References

Jan 21, 1977·Biochimica Et Biophysica Acta·J Garcia-SanchoH N Christensen
Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·J T HjelleS Udenfriend

Citations

Jul 4, 2001·Journal of Neuroscience Research·J Albrecht, M Dolińska
Aug 30, 2011·Neurotoxicity Research·Marta Skowrońska, J Albrecht
Dec 1, 1993·Neurochemistry International·F Joó
Mar 31, 2004·Molecular Genetics and Metabolism·C BachmannHugues Henry
Sep 21, 2002·Clinical Chemistry and Laboratory Medicine : CCLM·C Bachmann
Mar 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J P Colombo, C Bachmann

Related Concepts

Ammonia
Blood - Brain Barrier Anatomy
Brain
D-Glutamine
Microcirculation
Molecular Stereochemistry
PMS-Tryptophan

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