Stimuli-responsive poly(4-vinyl pyridine) hydrogel nanoparticles: synthesis by nanoprecipitation and swelling behavior

Journal of Colloid and Interface Science
Ana ArizagaRafael Piñol

Abstract

Stimuli-responsive polymer nanospheres of poly(4-vinyl pyridine) have been obtained using a very simple modified nanoprecipitation technique. This process is conducted without help of crosslinking or monomer polymerization, methods used until now for this purpose. The influence of the surfactant concentration used in the preparation on particle size, the stability and the swelling kinetics of these hydrogels are studied. Furthermore, the nanospheres are shown to be pH and ionic strength responsive, undergoing swelling with equilibration times in the range of days. Dynamic light scattering and scanning electron microscopy were used to determine the structure, size, dispersion and morphology of these materials. Due to their response to stimuli, these nanoparticles are of potential interest for a number of biomedical applications such as drug delivery or biosensors.

References

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Mar 22, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Damien DupinSteven M Baxter
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Citations

Sep 4, 2012·Carbohydrate Polymers·Alexandre T PaulinoElias B Tambourgi
Sep 4, 2015·Soft Matter·Efe Armagan, Gozde Ozaydin Ince
Sep 24, 2013·Carbohydrate Polymers·Mohammad Reza Vakili, Nahid Rahneshin
May 17, 2011·Journal of Colloid and Interface Science·Md Mahbubor RahmanAbdelhamid Elaissari
Jun 26, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Nia C BellAlexander G Shard
May 13, 2017·Macromolecular Rapid Communications·Xiaolin LiuMarek W Urban
Jul 4, 2020·International Journal of Nanomedicine·Adam KasińskiMarcin Sobczak
May 11, 2018·ACS Applied Materials & Interfaces·Milena Nadgorny, Amir Ameli

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