Stimulus-specific behavioral responses of zebrafish to a large range of odors exhibit individual variability.

BMC Biology
Florence KermenEmre Yaksi

Abstract

Odor-driven behaviors such as feeding, mating, and predator avoidance are crucial for animal survival. The neural pathways processing these behaviors have been well characterized in a number of species, and involve the activity of diverse brain regions following stimulation of the olfactory bulb by specific odors. However, while the zebrafish olfactory circuitry is well understood, a comprehensive characterization linking odor-driven behaviors to specific odors is needed to better relate olfactory computations to animal responses. Here, we used a medium-throughput setup to measure the swimming trajectories of 10 zebrafish in response to 17 ecologically relevant odors. By selecting appropriate locomotor metrics, we constructed ethograms systematically describing odor-induced changes in the swimming trajectory. We found that adult zebrafish reacted to most odorants using different behavioral programs and that a combination of a few relevant behavioral metrics enabled us to capture most of the variance in these innate odor responses. We observed that individual components of natural food and alarm odors do not elicit the full behavioral response. Finally, we show that zebrafish blood elicits prominent defensive behaviors similar t...Continue Reading

References

Feb 1, 1991·The Journal of Comparative Neurology·R K Lee, R C Eaton
Feb 20, 1982·The Journal of Comparative Neurology·C B KimmelW K Metcalfe
Mar 22, 1993·The Journal of Comparative Neurology·R K LeeS J Zottoli
Aug 24, 1999·Journal of Food Protection·B Ben-GigireyJ Barros-Velazquez
Mar 15, 1963·Experientia·W PFEIFFER
Feb 24, 2004·Chemical Senses·Sara M Lindsay, Richard G Vogt
Aug 9, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·A VitebskyK E Whitlock
Jan 13, 2006·Nature Chemical Biology·Peter W SorensenThomas R Hoye
Nov 4, 2006·Journal of Neuroscience Methods·Bradley N Johnson, Noam Sobel
Dec 26, 2006·Behavior Research Methods·Rachel Blaser, Robert Gerlai
Jul 3, 2007·The Journal of Experimental Biology·Harold A Burgess, Michael Granato
Jul 5, 2007·PLoS Biology·Emre YaksiRainer W Friedrich
Aug 23, 2008·Science·Julien BrechbühlMarie-Christine Broillet
Feb 24, 2009·Current Biology : CB·Jeffrey A RiffellJohn G Hildebrand
Mar 13, 2009·American Journal of Physiology. Renal Physiology·M H BraunS F Perry
Mar 24, 2009·Nature Neuroscience·Emre YaksiRainer W Friedrich
Apr 28, 2009·Nature·Julia L Semmelhack, Jing W Wang
Jun 6, 2009·Proceedings of the National Academy of Sciences of the United States of America·Tetsuya KoideYoshihiro Yoshihara
Aug 19, 2009·Annals of the New York Academy of Sciences·Kjell B Døving, Stine Lastein
Oct 30, 2010·Nature Protocols·Jonathan CachatAllan V Kalueff
Jan 5, 2011·PLoS Biology·Dominique DerjeanRéjean Dubuc
Mar 1, 2012·Current Biology : CB·Ajay S MathuruSuresh Jesuthasan
Apr 19, 2012·Scientific Reports·Kathrin SteckMarkus Knaden
Jun 6, 2012·Journal of Visualized Experiments : JoVE·Gabriela L PedrosoThemis R da Silveira
Jan 26, 2013·PloS One·Rodrigo Egydio BarretoGilson Luiz Volpato
Mar 26, 2013·Nature Methods·Misha B AhrensPhilipp J Keller
Apr 19, 2013·Frontiers in Neural Circuits·Florence KermenEmre Yaksi
Jun 20, 2013·Frontiers in Neural Circuits·Olivier MiratClaire Wyart
Jun 20, 2013·Frontiers in Neural Circuits·Akira Muto, Koichi Kawakami
Jul 4, 2013·Chemical Senses·Yasushi KiyokawaYuji Mori
Oct 1, 2013·Scientific Reports·Cornelia HinzGabriele Gerlach
Nov 13, 2013·Proceedings of the National Academy of Sciences of the United States of America·Ashiq HussainSigrun I Korsching
Dec 1, 1982·Journal of Chemical Ecology·B L FeinW L Roelofs
Apr 1, 2009·Animal Behaviour·Alison M BellKate L Laskowski
Apr 10, 2014·Nature Communications·Nobuhiko MiyasakaYoshihiro Yoshihara
Jan 28, 2015·General and Comparative Endocrinology·Tina Keller-CostaPeter C Hubbard
May 31, 2016·Nature Neuroscience·Yoichi YabukiYoshihiro Yoshihara
Jun 9, 2016·Nature Neuroscience·Florence KermenNathalie Mandairon
Jul 23, 2016·Frontiers in Physiology·Carolina E ReisenmanPablo G Guerenstein
Mar 23, 2017·Development, Growth & Differentiation·Keiko Umeda, Wataru Shoji
Apr 1, 2017·Scientific Reports·Ana I FaustinoRui F Oliveira

❮ Previous
Next ❯

Citations

Jan 7, 2021·Cell Reports·Shreyas M SuryanarayanaSten Grillner
Sep 21, 2020·Progress in Neuro-psychopharmacology & Biological Psychiatry·Suresh JesuthasanAjay Mathuru
Jan 31, 2021·Cell and Tissue Research·Florence KermenLaura Chalençon
Dec 19, 2020·Current Biology : CB·Kristian J HerreraFlorian Engert
Aug 28, 2020·Cell Reports·Fabrizio PalumboEmre Yaksi
Apr 30, 2021·STAR Protocols·Fabrizio PalumboEmre Yaksi
Aug 17, 2021·Environmental Science & Technology·Sarah KönemannColette Vom Berg
Aug 21, 2021·Current Biology : CB·Ewelina Magdalena BartoszekEmre Yaksi
Oct 27, 2021·The Journal of Comparative Neurology·Julián YáñezRamón Anadón

❮ Previous
Next ❯

Software Mentioned

Matlab

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

BioRxiv : the Preprint Server for Biology
Florence KermenEmre Yaksi
Journal of the American Pharmaceutical Association
N N TANYOLAC, J R EATON
Frontiers in Neural Circuits
Florence KermenEmre Yaksi
Nature Neuroscience
Agnieszka Grabska-BarwińskaPeter E Latham
© 2022 Meta ULC. All rights reserved