Stochastic dynamic causal modelling of fMRI data: should we care about neural noise?

NeuroImage
Jean DaunizeauKarl J Friston

Abstract

Dynamic causal modelling (DCM) was introduced to study the effective connectivity among brain regions using neuroimaging data. Until recently, DCM relied on deterministic models of distributed neuronal responses to external perturbation (e.g., sensory stimulation or task demands). However, accounting for stochastic fluctuations in neuronal activity and their interaction with task-specific processes may be of particular importance for studying state-dependent interactions. Furthermore, allowing for random neuronal fluctuations may render DCM more robust to model misspecification and finesse problems with network identification. In this article, we examine stochastic dynamic causal models (sDCM) in relation to their deterministic counterparts (dDCM) and highlight questions that can only be addressed with sDCM. We also compare the network identification performance of deterministic and stochastic DCM, using Monte Carlo simulations and an empirical case study of absence epilepsy. For example, our results demonstrate that stochastic DCM can exploit the modelling of neural noise to discriminate between direct and mediated connections. We conclude with a discussion of the added value and limitations of sDCM, in relation to its determi...Continue Reading

References

Sep 22, 1988·Nature·S Zeki, S Shipp
Jun 5, 2003·Chaos·Fathei Ali, Michael Menzinger
Sep 2, 2003·NeuroImage·K J FristonW Penny
Aug 25, 2004·Lancet Neurology·Steven LaureysNicholas D Schiff
Jun 2, 2005·Trends in Neurosciences·Mircea Steriade
Apr 21, 2006·NeuroImage·Khalid HamandiLouis Lemieux
Jun 6, 2006·Journal of Physiology, Paris·Marie-Elisabeth FaymonvilleSteven Laureys
Oct 24, 2006·NeuroImage·Karl FristonWill Penny
May 11, 2007·Magnetic Resonance Imaging·Louis LemieuxDavid Carmichael
Jun 5, 2007·Trends in Neurosciences·John R Huguenard, David A McCormick
Jul 17, 2007·NeuroImage·R J MoranK J Friston
Sep 22, 2007·NeuroImage·Klaas Enno StephanKarl J Friston
Jun 21, 2008·NeuroImage·Klaas Enno StephanKarl J Friston
Dec 5, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Alexander P LeffCathy J Price
Jun 30, 2009·PLoS Computational Biology·Mark D McDonnell, Derek Abbott
Oct 29, 2009·Physica D. Nonlinear Phenomena·J DaunizeauS J Kiebel
Mar 6, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hanneke E M den OudenKlaas E Stephan
Sep 8, 2010·NeuroImage·Stephen M SmithMark W Woolrich
Dec 25, 2010·NeuroImage·Karl J FristonKlaas E Stephan
Feb 12, 2011·NeuroImage·Baojuan LiKarl Friston
Apr 5, 2011·NeuroImage·Karl Friston, Will Penny
Nov 30, 2011·PLoS Computational Biology·Jean DaunizeauKlaas Stephan

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Citations

Oct 15, 2013·Lancet Neurology·Massimo FilippiMaria A Rocca
Jan 28, 2014·PLoS Computational Biology·Jean DaunizeauLionel Rigoux
Aug 27, 2013·PloS One·Francisco GómezQuentin Noirhomme
Feb 18, 2014·Australasian Physical & Engineering Sciences in Medicine·Baodong BaiHongyu Guo
Dec 3, 2014·NeuroImage·Adeel RaziKarl J Friston
Apr 25, 2015·Methods of Information in Medicine·P OsórioP Figueiredo
Nov 16, 2012·Human Brain Mapping·Liangsuo MaF Gerard Moeller
Jul 16, 2013·NeuroImage·Joshua Kahan, Tom Foltynie
May 7, 2013·NeuroImage·Alex FornitoMichael Breakspear
Sep 11, 2013·NeuroImage·L RigouxJ Daunizeau
May 27, 2015·NeuroImage·L Rigoux, J Daunizeau
May 24, 2014·European Psychiatry : the Journal of the Association of European Psychiatrists·D RadaelliF Benedetti
Apr 27, 2016·NeuroImage·Dirk Ostwald, Ludger Starke
Feb 20, 2016·PLoS Computational Biology·Vahid RahmatiStefan J Kiebel
Feb 24, 2017·Nature Neuroscience·Michael Breakspear
Jan 9, 2018·Journal of Cognitive Neuroscience·Stephen D Auger, Eleanor A Maguire
Oct 28, 2019·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Amirhossein JafarianKarl Friston
Nov 25, 2016·Frontiers in Human Neuroscience·Suchismita RayBharat B Biswal
Jun 17, 2020·Network Neuroscience·Matthieu GilsonAndrea Insabato
Mar 16, 2019·Frontiers in Neuroscience·Xuefei CaoXi Luo
Nov 14, 2020·NeuroImage·Valeria OlivaJonathan C W Brooks

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Software Mentioned

DCM

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