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Stochastic rearrangement of immunoglobulin variable-region genes in chicken B-cell development

Proceedings of the National Academy of Sciences of the United States of America

Aug 15, 1992

T BenatarMichael J H Ratcliffe

PMID: 1502173

Abstract

The molecular mechanism by which immunoglobulin (Ig) gene rearrangement occurs is highly conserved between mammalian and avian species. However, in avian species, an equivalent to the mammalian pre-B cell, which has undergone Ig heavy-chain gene rearrangement and expresses mu heavy chai...read more

Mentioned in this Paper

Embryo
Stochastic Processes
Bursa of Fabricius
Immunoglobulin Activity
Molecular Diagnostics Gene Rearrangement (Lab Test)
Pre-B Lymphocytes
Entire Embryo
Polymerase Chain Reaction Analysis
Immunoglobulins
Southern Blot Result
11
Paper Details
References
  • References25
  • Citations26
123
  • References25
  • Citations26
123

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Stochastic rearrangement of immunoglobulin variable-region genes in chicken B-cell development

Proceedings of the National Academy of Sciences of the United States of America

Aug 15, 1992

T BenatarMichael J H Ratcliffe

PMID: 1502173

DOI:

Abstract

The molecular mechanism by which immunoglobulin (Ig) gene rearrangement occurs is highly conserved between mammalian and avian species. However, in avian species, an equivalent to the mammalian pre-B cell, which has undergone Ig heavy-chain gene rearrangement and expresses mu heavy chai...read more

Mentioned in this Paper

Embryo
Stochastic Processes
Bursa of Fabricius
Immunoglobulin Activity
Molecular Diagnostics Gene Rearrangement (Lab Test)
Pre-B Lymphocytes
Entire Embryo
Polymerase Chain Reaction Analysis
Immunoglobulins
Southern Blot Result
11

Feeds With Similar Papers

B cell Differentiation

Depending on the signal received through the B cell receptor and other receptors, B cells differentiate into follicular or marginal zone B cells. Here is the latest research pertaining to this differentiation process.

Leukemia, T-Cell

T-cell leukemia includes various types of lymphoid leukemia that affect T cells. Here is the latest research on T-cell leukemia.

Related Papers

European Journal of Immunology

Expression of immunoglobulin genes in the avian embryo bone marrow revealed by retroviral transformation

European Journal of ImmunologyOctober 1, 1991
T BenatarMichael J H Ratcliffe
Paper Details
References
  • References25
  • Citations26
123
  • References25
  • Citations26
123

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