Stochastic resonance in the human vestibular system - Noise-induced facilitation of vestibulospinal reflexes

Brain Stimulation
M WuehrR Schniepp

Abstract

There is strong evidence that the presence of noise can enhance information processing in sensory systems via stochastic resonance (SR). To examine the presence of SR in human vestibulospinal reflex function. Healthy subjects were stimulated with 1 Hz sinusoidal GVS of varying amplitudes (0-1.9 mA). Coherence between GVS input and stimulation-induced motion responses was determined and psychometric function fits were subsequently used to determine individual vestibulospinal reflex thresholds. This procedure was repeated with additional application of imperceptible white noise GVS (nGVS). nGVS significantly facilitated the detectability of weak subthreshold vestibular inputs (p < 0.001) and thereby effectively lowered the vestibulospinal threshold in 90% of participants (p < 0.001, mean reduction: 17.5 ± 14.6%). This finding provides evidence for the presence of SR-dynamics in the human vestibular system and gives a functional explanation for previously observed ameliorating effects of low-intensity vestibular noise stimulation on balance control in healthy subjects and patients with vestibular hypofunction.

Citations

Mar 7, 2018·Journal of Neurology·Matthias ErtlM Dieterich
Apr 18, 2019·Journal of Neurophysiology·Julia DlugaiczykHans Straka
Mar 14, 2019·Journal of Neurophysiology·Nolan Herssens, Christopher McCrum
Aug 21, 2019·Orphanet Journal of Rare Diseases·Chisato FujimotoToshihisa Murofushi
Nov 8, 2019·PloS One·Mujda NooristaniFrançois Champoux
Mar 17, 2018·Frontiers in Neurology·Aram KeywanKlaus Jahn
Dec 20, 2018·Current Opinion in Neurology·Jean-Philippe Guyot, Angelica Perez Fornos
Nov 9, 2018·Frontiers in Neurology·Chisato FujimotoShinichi Iwasaki
Jan 19, 2021·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Y J Wadop NgouongoT C Kofané
Dec 10, 2020·Journal of Neurophysiology·Mujda NooristaniFrançois Champoux
Nov 17, 2020·Frontiers in Human Neuroscience·Yasuto InukaiHideaki Onishi
Aug 6, 2019·NeuroImage. Clinical·Christoph HelmchenAndreas Sprenger
Apr 20, 2021·Frontiers in Neuroscience·Jamie L VorosTorin K Clark

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addison Disease

Addison's disease, also known as primary adrenal insufficiency and hypocortisolism, is a long-term endocrine disorder in which the adrenal glands do not produce enough steroid hormones. Discover the latest research on Addison's disease here.