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Stochasticity and negative feedback lead to pulsed dynamics and distinct gene activity patterns

bioRxiv

Dec 3, 2014

Samuel ZambranoNacho Molina

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Abstract

Gene expression is an inherently stochastic process that depends on the structure of the biochemical regulatory network in which the gene is embedded. Here we study the interplay between stochastic gene switching and the widespread negative feedback regulatory loop. Using a simple hybri...read more

Mentioned in this Paper

Gene Expression
Gene Activation
Patterns
Physiologic Pulse
Structure
Widespread
Genes
Gene Regulatory Networks
Genes, Switch
5
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  • Stochasticity and negative feedback lead to pulsed dynamics and distinct gene activity patterns

    bioRxiv

    Dec 3, 2014

    Samuel ZambranoNacho Molina

    PMID: 990011734

    DOI: 10.1101/011734

    Abstract

    Gene expression is an inherently stochastic process that depends on the structure of the biochemical regulatory network in which the gene is embedded. Here we study the interplay between stochastic gene switching and the widespread negative feedback regulatory loop. Using a simple hybri...read more

    Mentioned in this Paper

    Gene Expression
    Gene Activation
    Patterns
    Physiologic Pulse
    Structure
    5

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