Strategic plan for pediatric respiratory diseases research: an NHLBI working group report.

Proceedings of the American Thoracic Society
Mario CastroRosalind J Wright

Abstract

The Division of Lung Diseases of the National Heart, Lung, and Blood Institute (NHLBI) recently held a workshop to identify gaps in our understanding and treatment of childhood lung diseases and to define strategies to enhance translational research in this field. Leading experts with diverse experience in both laboratory and patient-oriented research reviewed selected areas of pediatric lung diseases, including perinatal programming and epigenetic influences; mechanisms of lung injury, repair, and regeneration; pulmonary vascular disease; sleep and control of breathing; and the application of novel translational methods to enhance personalized medicine. This report summarizes the proceedings of this workshop and provides recommendations for emphasis on targeted areas for future investigation. The priority areas identified for research in pediatric pulmonary diseases included: (1) epigenetic and environmental influences on lung development that program pediatric lung diseases; (2) injury, regeneration, and repair in the developing lung; (3) pulmonary vascular disease in children; (4) development and adaptation of ventilatory responses to postnatal life; (5) nonatopic wheezing: aberrant large airway development or injury?; (6) s...Continue Reading

Citations

Aug 21, 2012·Maternal and Child Health Journal·Elizabeth C ParsonsAlyson J Littman
Jul 5, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Lincoln S SmithThomas R Martin
Nov 26, 2010·Immunology and Allergy Clinics of North America·Rosalind J Wright
Jan 19, 2010·Biological Psychology·Rosalind J Wright
Apr 17, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Karin B YeattsDarren A DeWalt

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