PMID: 6985308Apr 1, 1982Paper

Strategies for analysing ecological health data: models of the biological risk of individuals

Statistics in Medicine
K G MantonW Riggan

Abstract

Frequently, the analysis of environmental health hazards using ecological data does not involve explicit recognition of the difficulties in translating health effects expressed in the aggregate to the health risks of individuals. We discuss these difficulties and suggest the need for the appropriate conceptualization of risk mechanisms at the individual level and of the population processes that determine the form in which these risk mechanisms are expressed in aggregate data. To illustrate the implications of these concepts we develop a biologically motivated model of lung cancer risk and apply it to both national and county data. In addition, to measure the total health effects of the long term elevation or depression of lung cancer incidence rates, we calculate prevalence distributions from the time series analysis of incidence patterns in county data.

References

Jul 1, 1978·Journal of the National Cancer Institute·S H Moolgavkar
Aug 1, 1979·Computers and Biomedical Research, an International Journal·K G Manton, E Stallard
Mar 1, 1976·International Journal of Epidemiology·G W Griffith
Dec 1, 1970·Clinical Obstetrics and Gynecology·J O ArchambeauD Lubell
Jan 15, 1969·International Journal of Cancer. Journal International Du Cancer·P J CookS A Fellingham
May 1, 1980·Demography·K G Manton, E Stallard
Aug 29, 1980·Science·R J Smith
Mar 1, 1954·British Journal of Cancer·P ARMITAGE, R DOLL
Jul 12, 1965·JAMA : the Journal of the American Medical Association·E M HERSHE J FREIREICH

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Citations

Aug 1, 1982·Computers and Biomedical Research, an International Journal·K G Manton, E Stallard
Apr 1, 1986·Computers and Biomedical Research, an International Journal·K G MantonM A Woodbury
May 1, 1985·Environmental Health Perspectives·K G MantonW B Riggan
Nov 1, 1988·Statistics in Medicine·O O Aalen

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