Strategies for improving the early diagnosis of keratoconus

Clinical Optometry
Yue Shi

Abstract

To diagnose keratoconus at its earliest stage is meaningful in order to avoid refractive surgery in the eye, which may lead to further damage in the abnormal cornea structure and consequently cause iatrogenic ectasia. In this article, the following aspects of detecting earliest stage of keratoconus were reviewed: 1) nomenclature of the earliest forms of keratoconus; 2) diagnosis of keratoconus using curvature-based topography (also known as Placido-based topography, ie, videokeratography) as a traditional method and elevation-based topography as a new method which has gained popularity in recent years; and 3) other methods analyzing keratoconus cornea like corneal biomechanics and wavefront sensing. Elevation-based topography using either Scheimpflug imaging techniques or slit-scanning imaging techniques has shown to be advantageous over the curvature-based topography in detecting keratoconus at its earliest stage. Posterior elevation of the cornea is notified to enhance the sensitivity and specificity of detection if used along with the measurements of anterior surface of the cornea. Cornea biomechanics analysis and wavefront sensing also revealed differences between normal eyes and keratoconic eyes in their earliest stage. Co...Continue Reading

Citations

Sep 20, 2018·Ocular Immunology and Inflammation·Mercedes MalfeitoIsabel Lema
Apr 4, 2021·Sensors·Hanan A Hosni Mahmoud, Hanan Abdullah Mengash
Aug 3, 2021·BMJ Open Ophthalmology·Xu ChenYalin Zheng
Jul 24, 2021·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Stefan J LangT Reinhard
Nov 24, 2021·European Journal of Ophthalmology·Abdelrahman Salman Rafea Shaaban

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BETA
KISA
imaging techniques

Software Mentioned

Orbscan
Pentacam

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