Strategies for the scale-up of antiretroviral therapy in South Africa through health system optimization

The Journal of Infectious Diseases
Pierre M BarkerDonald M Berwick

Abstract

In the face of the massive burden created by human immunodeficiency virus/acquired immunodeficiency syndrome and other infectious diseases, developing nations must find ways to rapidly begin treatment for infected persons. Although infusions of personnel, supplies, and diagnostics would make a major contribution to expanding the capacity to treat these diseases, the lack of these resources creates a long-term challenge, and there is a need for additional approaches to spread effective interventions that can leverage existing resources and the much-needed infusions of new resources. This article describes one such approach-applied in several forms in South Africa-that aims to significantly increase the number of patients receiving antiretroviral therapy.

References

Jan 5, 1989·The New England Journal of Medicine·D M Berwick
May 8, 2004·BMJ : British Medical Journal·Donald M Berwick
Apr 13, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C William WesterRichard G Marlink
Jun 9, 2005·International Journal of Epidemiology·Matthias EggerPaolo Miotti
Dec 2, 2005·PLoS Medicine·Motasim BadriEduard J Beck
Apr 4, 2006·Sexually Transmitted Infections·B ChelugetJ Stover
Apr 4, 2006·Sexually Transmitted Infections·A MahomvaS Hader
Jun 3, 2006·BMJ : British Medical Journal·C Joseph McCannonAlexander G Nazem
Aug 15, 2006·JAMA : the Journal of the American Medical Association·Jeffrey S A StringerMoses Sinkala
Aug 18, 2006·The New England Journal of Medicine·Jim Yong Kim, Paul Farmer
Sep 7, 2006·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Ulla M Idänpään-HeikkiläJack V Tu
Jan 3, 2008·AIDS·Sarah BernaysTony Barnett

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Citations

Oct 19, 2010·Health Policy and Planning·George ShakarishviliRifat Atun
May 28, 2013·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Kedar S MatePierre M Barker
Dec 1, 2012·Globalization and Health·Duncan Smith-Rohrberg MaruSona Shilpakar
Jun 3, 2014·Implementation Science : IS·Kenneth SherrUNKNOWN With input from the SAIA Study Team
Oct 9, 2015·The British Journal of Psychiatry : the Journal of Mental Science·Inge PetersenVikram Patel
Apr 14, 2012·Best Practice & Research. Clinical Obstetrics & Gynaecology·Tanuja N Gengiah, Quarraisha Abdool Karim
Nov 19, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Pierre M BarkerNigel Rollins
Mar 22, 2013·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Wilbroda NgidiKedar S Mate
Sep 8, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Georgette Adjorlolo-JohnsonRichard Marlink
Feb 11, 2010·Health Policy and Planning·Elena Tkatchenko-SchmidtAdrian Renton
Mar 29, 2013·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Kerry E UebelEdwin Wouters

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