Strategies to increase the resectability of hepatocellular carcinoma

World Journal of Hepatology
Wong Hoi She, Kenneth Sh Chok

Abstract

Hepatocellular carcinoma (HCC) is best treated by liver transplantation, but the applicability of transplantation is greatly limited. Tumor resection in partial hepatectomy is hence resorted to. However, in most parts of the world, only 20%-30% of HCCs are resectable. The main reason for such a low resectability is a future liver remnant too small to be sufficient for the patient. To allow more HCC patients to undergo curative hepatectomy, a variety of ways have been developed to increase the resectability of HCC, mainly ways to increase the future liver remnants in patients through hypertrophy. They include portal vein embolization, sequential transarterial chemoembolization and portal vein embolization, staged hepatectomy, two-staged hepatectomy with portal vein ligation, and Associating Liver Partition and Portal Vein Ligation in Staged Hepatectomy. Herein we review, describe and evaluate these different ways, ways that can be life-saving.

References

Oct 1, 1986·World Journal of Surgery·H KinoshitaS Kubo
Mar 14, 1996·The New England Journal of Medicine·V MazzaferroL Gennari
Jan 1, 1997·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·K YanagaK Sugimachi
Nov 15, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K KubotaT Takayama
Mar 17, 1999·Annals of Surgery·S T FanJ Wong
Mar 30, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H ImamuraS Kawasaki
Feb 3, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K Jungermann, T Kietzmann
May 11, 2000·Digestive Surgery·C Couinaud
Jun 8, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·F Y YaoJ P Roberts
Jul 10, 2001·Journal of the American College of Surgeons·J BelghitiR Kianmanesh
Aug 2, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N KokudoY Kato
Aug 17, 2001·Archives of Surgery·T TakayamaK Hasegawa
Feb 1, 2003·Annals of Surgery·Olivier FargesAlain Sauvanet
Mar 26, 2003·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Margo ShoupYuman Fong
Dec 12, 2003·Lancet·Josep M LlovetJordi Bruix
Jan 10, 2004·Langenbeck's Archives of Surgery·Hiroshi ShimadaShinji Togo
Mar 9, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Chung-Mau LoJohn Wong
Mar 26, 2004·Surgery·Eddie K AbdallaJean-Nicolas Vauthey
Jan 14, 2005·Gut·M J SchindlUNKNOWN Edinburgh Liver Surgery and Transplantation Experimental Research Group (eLISTER)
Mar 9, 2005·Journal of Hepato-biliary-pancreatic Surgery·Ronnie T Poon, Sheung Tat Fan
Jun 24, 2005·American Journal of Surgery·Emma J MullinGuy J Maddern
Nov 1, 2005·Journal of Hepato-biliary-pancreatic Surgery·Sheung Tat Fan, Chi Leung Liu
Sep 2, 2006·Annals of Surgical Oncology·Chusilp CharnsangavejMichael A Choti
Feb 23, 2007·The British Journal of Surgery·D ZorziE K Abdalla

❮ Previous
Next ❯

Citations

Aug 25, 2017·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Bin LiXiaoqing Jiang
Dec 7, 2016·Annals of Surgical Oncology·Jian ZhengRonald P DeMatteo
May 5, 2020·British Journal of Cancer·Valtteri KairaluomaOlli Helminen
Nov 26, 2020·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Prasad WagleParesh Varty
Mar 6, 2021·Expert Review of Gastroenterology & Hepatology·Josephine TsangThomas Yau
Apr 24, 2021·Minerva Surgery·Valtteri KairaluomaOlli Helminen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.