PMID: 26344745DOI: 10.3390/vaccines2030549Jan 1, 2014Paper
Strategy for Designing a Synthetic Tumor Vaccine: Multi-Component, Multivalency and Antigen Modification
Vaccines
Zhi-Hua HuangYan-Mei Li
Abstract
Synthetic tumor vaccines have been proven to be promising for cancer immunotherapy. However, the limitation of the specificity and efficiency of the synthetic tumor vaccines need further improvements. To overcome these difficulties, additional tumor-associated targets need to be identified, and optimized structural designs of vaccines need to be elaborated. In this review, we summarized the main strategies pursued in the design of synthetic tumor vaccines, such as multi-component, multivalency, antigen modification and other possible ways to improve the efficiency of synthetic tumor vaccines.
References
Dec 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·J P Tam, Y A Lu
Mar 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·H NakadaI Yamashina
Apr 1, 1995·The Journal of Cell Biology·J WesselingJ Hilkens
Nov 24, 1999·Immunological Reviews·R F Wang, S A Rosenberg
Mar 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·V KudryashovK O Lloyd
Jul 31, 2001·Nature Immunology·S AkiraT Kaisho
Mar 23, 2002·Biochimica Et Biophysica Acta·Tsuneyasu Kaisho, Shizuo Akira
Aug 23, 2002·Cancer Immunology, Immunotherapy : CII·Stephen WardStephen Todryk
Sep 25, 2002·Microbes and Infection·Clett ErridgeIan R Poxton
Oct 31, 2002·Nature Immunology·Gavin P DunnRobert D Schreiber
Sep 5, 2003·Oncogene·Yongqing LiDonald Kufe
May 26, 2004·Bioorganic & Medicinal Chemistry·Jiahong NiLai-Xi Wang
Jul 2, 2004·Nature Reviews. Immunology·Shizuo Akira, Kiyoshi Takeda
Jul 2, 2004·Nature Reviews. Immunology·Bruno Lemaitre
Jul 29, 2004·Proceedings of the National Academy of Sciences of the United States of America·Stacy J Keding, Samuel J Danishefsky
Mar 19, 2005·Nature Reviews. Cancer·Weiping Zou
Apr 22, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Govind RagupathiPhilip O Livingston
Jul 12, 2005·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Uwe KarstenSteffen Goletz
Oct 26, 2005·Angewandte Chemie·Sebastian DziadekHorst Kunz
Feb 24, 2006·Journal of the American Chemical Society·Govind RagupathiSamuel J Danishefsky
Jul 27, 2006·Nature Reviews. Immunology·Thomas A Waldmann
Feb 24, 2007·Nature Reviews. Immunology·Giorgio Trinchieri, Alan Sher
Apr 27, 2007·Nature·Danica P Galonić, David Y Gin
Jun 15, 2007·Nature Reviews. Microbiology·Bruno Guy
Jun 16, 2007·Organic & Biomolecular Chemistry·Jingsong WangLai-Xi Wang
Sep 4, 2007·Nature Chemical Biology·Sampat IngaleGeert-Jan Boons
Oct 16, 2007·Angewandte Chemie·Francesca BoatoJohn A Robinson
Nov 21, 2007·Cancer Biology & Therapy·Ravibhushan Singh, Dilip Bandyopadhyay
Apr 11, 2008·Critical Reviews in Oncology/hematology·Sharmila Pejawar-Gaddy, Olivera J Finn
Jun 28, 2008·Cancer Immunology, Immunotherapy : CII·Ilham BettahiLbachir BenMohamed
Aug 16, 2008·Angewandte Chemie·Ulrika WesterlindHorst Kunz
Jan 16, 2009·Chembiochem : a European Journal of Chemical Biology·Sampat IngaleGeert-Jan Boons
Mar 4, 2009·Journal of the American Chemical Society·Jianglong ZhuSamuel J Danishefsky
Jun 13, 2009·Journal of the American Chemical Society·Jianglong ZhuSamuel J Danishefsky
Aug 18, 2009·Angewandte Chemie·Anton KaiserHorst Kunz
Sep 15, 2009·Journal of the American Chemical Society·Insik JeonSamuel J Danishefsky
Sep 22, 2009·Current Opinion in Chemical Biology·Zhongwu Guo, Qianli Wang
Nov 17, 2009·Trends in Biochemical Sciences·Shantibhusan SenapatiSurinder K Batra
Dec 22, 2009·Bioconjugate Chemistry·Mallikarjuna Reddy PuttaSudhir Agrawal
Mar 18, 2010·Chemical Communications : Chem Comm·Hamilton KakwereSébastien Perrier
May 8, 2010·Angewandte Chemie·Anton KaiserHorst Kunz
Jul 10, 2010·Proceedings of the National Academy of Sciences of the United States of America·Xiangming LiMoriya Tsuji
Jul 20, 2010·Immunotherapy·Richard E BeatsonJoy M Burchell
Sep 8, 2010·Angewandte Chemie·Mariusz SkwarczynskiIstvan Toth
Sep 9, 2010·Expert Review of Vaccines·Moses O OyewumiZhengrong Cui
Sep 30, 2010·Angewandte Chemie·Anja Hoffmann-RöderHorst Kunz
Oct 16, 2010·Nature Reviews. Immunology·Martin F Bachmann, Gary T Jennings
Nov 18, 2010·Journal of the American Chemical Society·Sourav SarkarSteven J Sucheck
Dec 3, 2010·ACS Chemical Biology·Fan YangXin-Shan Ye
Dec 7, 2010·Chembiochem : a European Journal of Chemical Biology·Arin GhasparianJohn A Robinson
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Citations
Jan 26, 2017·Organic Letters·Xu-Guang YinJun Guo
Mar 8, 2018·Medicinal Research Reviews·Meng-Man WeiXin-Shan Ye
Oct 1, 2016·Small·Arpad KarsaiGang-Yu Liu
Sep 12, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Nicole BrooksGeoffrey A Pietersz
Sep 14, 2017·Scientific Reports·Zhifang ZhouZhongwu Guo
Sep 29, 2017·Bioconjugate Chemistry·Hamilton KakwereKatherine W Ferrara
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