PMID: 24335008Dec 18, 2013Paper

Strategy of operative treatment of hyperparathyroidism using US scan and (99m)Tc-MIBI SPECT/CT

Endocrine Journal
Satoru NodaKosei Hirakawa

Abstract

We evaluated the efficacy of technetium-sestamibi ((99m) Tc-MIBI) SPECT/CT for planning parathyroidectomy in cases with primary hyperparathyroidism (pHPT), comparing with planar scintigraphy and ultrasound (US), in an aim to establish the proper surgical strategy according to the preoperative imaging studies. A retrospective review of consecutive 75 pHPT patients who had been operated on was conducted. The results of preoperative imaging modalities and the operative finding were analyzed. Seven cases were found to have multiple hyperplastic glands, and no responsible gland was found in three cases. Four cases underwent only US scan for preoperative imaging. Remaining 61 cases were found to have single adenoma, and were included in the evaluation of localization imaging. US scan, (99m) Tc-MIBI planar scan and (99m) Tc-MIBI SPECT/CT showed accurate localization in 77.0% (47/61), 75.4% (46/61) and 88.5% (46/52) of the evaluable cases, respectively. US and (99m) Tc-MIBI planar scan demonstrated consistent result in 42 cases (68.9%), and those cases showed accurate localization in 90.5% (38/42). When both US and (99m) Tc-MIBI SPECT/CT was consistent, all 37 lesions had been correctly indicated. No clinico-pathological features were ...Continue Reading

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Citations

Aug 23, 2017·The Indian Journal of Surgery·Zeynep Gozde OzkanYesim Erbil
Jul 6, 2021·Revista Española De Medicina Nuclear E Imagen Molecular·F CarralC Ayala
Nov 29, 2020·Revista española de medicina nuclear e imagen molecular·F CarralC Ayala

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