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Stratified medicine: strategic and economic implications of combining drugs and clinical biomarkers

Nature Reviews. Drug Discovery

Mar 24, 2007

Mark R TrusheimFrank L Douglas

Abstract

The potential to use biomarkers for identifying patients that are more likely to benefit or experience an adverse reaction in response to a given therapy, and thereby better match patients with therapies, is anticipated to have a major effect on both clinical practice and the developmen...read more

Mentioned in this Paper

Drug Industry
Pharmacotherapy
Pharmaceutical Preparations
Decision Making, Shared
Viral Markers
3
392
Paper Details
References
  • References13
  • Citations181
12
  • References13
  • Citations181
12345...

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Stratified medicine: strategic and economic implications of combining drugs and clinical biomarkers

Nature Reviews. Drug Discovery

Mar 24, 2007

Mark R TrusheimFrank L Douglas

PMID: 17380152

DOI: 10.1038/nrd2251

Abstract

The potential to use biomarkers for identifying patients that are more likely to benefit or experience an adverse reaction in response to a given therapy, and thereby better match patients with therapies, is anticipated to have a major effect on both clinical practice and the developmen...read more

Mentioned in this Paper

Drug Industry
Pharmacotherapy
Pharmaceutical Preparations
Decision Making, Shared
Viral Markers
3
392

Similar Papers Found In These Feeds

Decision Making & Cognitive Aging

While abilities like vocabulary resist aging, other abilities such as memory, decision-making, and reasoning, gradually decline. Here is the latest research on decision-making and cognitive aging.

Drug & Digital Interventions

This feed describes how digital interventions, which are digital and mobile technologies used to support health system needs, can complement and improve pharmacotherapy in disease management. Discover the latest research on drug and digtial intervention here,

Related Papers

Nature Reviews. Drug Discovery

Quantifying factors for the success of stratified medicine

Nature Reviews. Drug DiscoveryNovember 1, 2011
Mark R TrusheimMichael C Palmer
Expert Review of Molecular Diagnostics

Are we approaching the post-blockbuster era? Pharmacodiagnostics and rational drug development

Expert Review of Molecular DiagnosticsNovember 13, 2008
Jan Trøst Jørgensen
Paper Details
References
  • References13
  • Citations181
12
  • References13
  • Citations181
12345...
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