Stratifying Minimal Versus Severe Pain in Knee Osteoarthritis Using a Musculoskeletal Ultrasound Protocol

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Mary Monica Bernardo-BuenoFrancisco De Los Reyes

Abstract

The aim of this cross-sectional correlational study was to determine the association of pain with morphologic and inflammatory sonographic findings in patients with knee osteoarthritis. A total of 113 participants with knee osteoarthritis were assessed using visual analog scale pain score and sonography. Ultrasound evaluation included morphologic changes (ie, articular cartilage degeneration, medial and lateral meniscal protrusion, and presence of osteophytes on the joint margins) and inflammatory changes (ie suprapatellar effusion and/or synovitis, Baker cyst, superficial and deep infrapatellar effusion, pes anserine tendinopathy, and Hoffa panniculitis). Cluster analysis via Ward's method grouped patients with minimal pain (visual analog scale score, 0-4) and with substantial pain (visual analog scale score, 5-10). Stepwise logistic regression yielded 5 variables that significantly explained the variation in the probability of perceived substantial pain at 10% level of significance: lateral cartilage clarity (LCC; P = .025), medial cartilage clarity (MCC; P = .20), medial cartilage thickness (MCT; P = .041), medial meniscus protrusion (MMP) (P = .029), and osteophytes at medial femoral margin (P = .082), with 63% overall pred...Continue Reading

References

Dec 1, 1957·Annals of the Rheumatic Diseases·J H KELLGREN, J S LAWRENCE
Dec 3, 2003·Annals of the Rheumatic Diseases·K M JordanUNKNOWN Standing Committee for International Clinical Studies Including Therapeutic Trials ESCISIT
Jun 1, 2006·Osteoarthritis and Cartilage·E de Miguel MendietaE Martín Mola
Nov 2, 2006·Current Medical Research and Opinion·Alfonso E Bello, Steffen Oesser
Aug 8, 2008·Annals of the Rheumatic Diseases·E NaredoI Sáenz-Navarro
Sep 2, 2008·Osteoarthritis and Cartilage·I MöllerA Iagnocco
Feb 5, 2010·Best Practice & Research. Clinical Rheumatology·Annamaria Iagnocco
Aug 12, 2010·Clinics in Geriatric Medicine·Yuqing Zhang, Joanne M Jordan
Mar 2, 2011·Clinical Rheumatology·Başkan Bedriye MermerciHatice Bodur
Apr 8, 2011·BMC Musculoskeletal Disorders·Ajay M AbrahamFraser Birrell
Jun 3, 2011·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jonathan K KazamRonald S Adler
Jun 8, 2011·Annals of the Rheumatic Diseases·Martin EnglundMichael C Nevitt
Jul 31, 2012·Rheumatology·Annamaria IagnoccoGuido Valesini
Apr 19, 2013·Rheumatology·Carlos AcebesGabriel Herrero-Beaumont
Apr 8, 2014·Rheumatology·Karen BeversAlfons Abigael den Broeder
Oct 4, 2014·Osteoarthritis and Cartilage·B F RieckeH Bliddal
Jun 20, 2015·Clinical Rheumatology·Ahmed Abdel Khalek Abdel Razek, Sherif Refaat El-Basyouni
Jan 29, 2017·Topics in Cognitive Science·Wayne D Gray
Feb 6, 2017·Arthritis Research & Therapy·Alexander Mathiessen, Philip G Conaghan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.