Strengthening And stretching for Rheumatoid Arthritis of the Hand (SARAH). A randomised controlled trial and economic evaluation

Health Technology Assessment : HTA
Mark A WilliamsSarah E Lamb

Abstract

The effectiveness of exercise for improving hand and wrist function in people with rheumatoid arthritis (RA) is uncertain. The study aims were (1) to estimate the clinical effectiveness and cost-effectiveness of adding an optimised exercise programme for hands and upper limbs to standard care for patients with RA; and (2) to qualitatively describe the experience of participants in the trial with a particular emphasis on acceptability of the intervention, exercise behaviours and reasons for adherence/non-adherence. A pragmatic, multicentred, individually randomised controlled trial with an embedded qualitative study. Outcome assessors were blind to group assignment and independent of treatment delivery. Seventeen NHS trusts in England comprising 21 rheumatology and therapy departments. Adults with RA who had pain and dysfunction of the hands and/or wrists and had been on stable medication for at least 3 months. Patients were excluded if they were under 18 years old, had undergone upper limb surgery/fracture in the last 6 months, were on a waiting list for upper limb surgery or were pregnant. Usual care or usual care plus an individualised exercise programme. Usual care consisted of joint protection education, general exercise ad...Continue Reading

References

Jun 1, 1992·Arthritis Care and Research : the Official Journal of the Arthritis Health Professions Association·B DellhagA Bjelle
Feb 1, 1991·Current Opinion in Rheumatology·A L Osterman, J Hood
Mar 1, 1987·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·M A Wehbé
Jan 1, 1986·Annales De Chirurgie De La Main : Organe Officiel Des Sociétés De Chirurgie De La Main·A Kapandji
Jan 1, 1982·Medicine and Science in Sports and Exercise·G A Borg
Mar 1, 1995·Arthritis Care and Research : the Official Journal of the Arthritis Health Professions Association·B Dellhag, C S Burckhardt
May 1, 1993·British Journal of Rheumatology·S W BrightonC A van der Merwe
Jan 1, 1996·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·W J RejeskiS Shumaker
Jan 1, 1996·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·E B Stern
Jul 1, 1997·The Journal of Psychology·T Toray, E Cooley
Jul 17, 1998·British Journal of Rheumatology·C H Van den EndeJ M Hazes
Aug 26, 1998·The Journal of Hand Surgery·K C ChungR A Hayward
Jun 6, 1996·Health Policy·R Brooks
Dec 8, 1996·Journal of Health Services Research & Policy·C Jenkinson, R Layte
Oct 8, 1999·Arthritis Care and Research : the Official Journal of the Arthritis Health Professions Association·B Dellhag, A Bjelle
May 24, 2000·Controlled Clinical Trials·J M Lachin
Nov 30, 2000·Arthritis Care and Research : the Official Journal of the Arthritis Health Professions Association·S C LinekerA Wilkins
Aug 15, 2001·Arthritis and Rheumatism·A I BuljinaT B Hunter
Nov 2, 2001·Archives of Physical Medicine and Rehabilitation·Q W SmithJ K Roberts
Dec 6, 2001·Archives of Psychiatric Nursing·V G Sinclair
Feb 6, 2002·Medicine and Science in Sports and Exercise·William J KraemerUNKNOWN American College of Sports Medicine
Feb 13, 2002·Arthritis and Rheumatism·UNKNOWN American College of Rheumatology Subcommittee on Rheumatoid Arthritis Guidelines
May 3, 2002·Journal of Neurology·Crispin JenkinsonUNKNOWN ALS-HPS Steering Group. Amyotrophic Lateral Sclerosis Health Profile Study
Apr 30, 2003·Health Economics·Andrew BriggsPhilip Clarke
Jun 26, 2003·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·J A UnderwoodR F Keate
Aug 14, 2003·Best Practice & Research. Clinical Rheumatology·Thea P M Vliet Vlieland
May 14, 2004·Current Opinion in Pharmacology·Simon M Blake, Barbara A Swift
May 27, 2004·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Jean Wessel
Aug 11, 2004·Best Practice & Research. Clinical Rheumatology·Alison Hammond
Aug 21, 2004·Medical Care·John E Brazier, Jennifer Roberts

❮ Previous
Next ❯

Citations

Apr 8, 2018·Rheumatology International·Susie C HigginsRodney Hughes
Aug 1, 2018·The Cochrane Database of Systematic Reviews·Mark A WilliamsSarah E Lamb
Jun 17, 2016·The Journal of Bone and Joint Surgery. American Volume·Theodore J Choma, Darrel S Brodke

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved