Strengthening the reliability and credibility of observational epidemiology studies by creating an Observational Studies Register

Journal of Clinical Epidemiology
Gerard M H SwaenJohn Doe

Abstract

To evaluate the need for the creation of a system in which observational epidemiology studies are registered; an Observational Studies Register (OSR). The current scientific process for observational epidemiology studies is described. Next, a parallel is made with the clinical trials area, where the creation of clinical trial registers has greatly restored and improved their credibility and reliability. Next, the advantages and disadvantages of an OSR are compared. The advantages of an OSR outweigh its disadvantages. The creation of an OSR, similar to the existing Clinical Trials Registers, will improve the assessment of publication bias and will provide an opportunity to compare the original study protocol with the results reported in the publication. Reliability, credibility, and transparency of observational epidemiology studies are strengthened by the creation of an OSR. We propose a structured, collaborative, and coordinated approach for observational epidemiology studies that can provide solutions for existing weaknesses and will strengthen credibility and reliability, similar to the approach currently used in clinical trials, where Clinical Trials Registers have played a key role in strengthening their scientific value.

References

Mar 16, 1979·JAMA : the Journal of the American Medical Association·C HogstedtB Wadman
May 16, 1991·The New England Journal of Medicine·K SteenlandS Nowlin
Jan 1, 1987·Statistics in Medicine·R J Simes
Jul 14, 1995·Science·G Taubes
Nov 24, 1999·JAMA : the Journal of the American Medical Association·D Rennie
Nov 2, 2001·International Journal of Epidemiology·G G SwaenL G van Amelsvoort
Jul 24, 2003·JAMA : the Journal of the American Medical Association·Monika K KrzyzanowskaIan F Tannock
Nov 20, 2003·JAMA : the Journal of the American Medical Association·Giovanni Della Cioppa, Jean-Jacques Garaud
Sep 16, 2004·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Catherine De AngelisUNKNOWN International Committee of Medical Journal Editors
May 24, 2005·Archives of Disease in Childhood·H M SammonsM Bonati
Oct 19, 2006·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·David L Turpin
Jul 10, 2008·Journal of the National Cancer Institute·Paolo BoffettaWilliam J Blot
Dec 20, 2008·Occupational and Environmental Medicine·D R JonesL Rushton

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Citations

Dec 12, 2012·The American Journal of Clinical Nutrition·Michelle M Bohan BrownDavid B Allison
Sep 20, 2015·Journal of Clinical Epidemiology·Stefania BocciaJohn P A Ioannidis
Jul 15, 2015·Journal of Clinical Epidemiology·Lex M Bouter
Sep 3, 2013·Journal of Clinical Epidemiology·J André Knottnerus, Peter Tugwell
Mar 1, 2012·Journal of Clinical Epidemiology·J André Knottnerus, Peter Tugwell
Feb 14, 2019·Diabetes/metabolism Research and Reviews·Wenning FuShiyi Cao

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