Streptococcal cell wall arthritis

Current Protocols in Immunology
R L Wilder

Abstract

Streptococcal cell wall (SCW) arthritis in rats is an experimentally-induced inflammatory model with many features that resemble rheumatoid arthritis (RA) in humans. In this unit, Lewis rats are injected with an aqueous suspension of Group A SCW streptococcal cell wall peptidoglycan-polysaccharide polymers (SCW PG-PS) and observed for the development of arthritis. The resulting arthritis is biphasic. An acute phase typically develops within 48 hr, followed 10 to 21 days later by a chronic phase which persists for months. Support protocols are included for preparing Group A PG-PS and measuring PG-PS concentration.

References

Dec 1, 1977·The Journal of Experimental Medicine·W J CromartieC H Yang
Jun 16, 1975·European Journal of Biochemistry·R LotanD Mirelman
Dec 1, 1992·The Journal of Clinical Investigation·L J CroffordR L Wilder
May 1, 1992·Clinical and Experimental Immunology·M F van den BroekW B van den Berg
Jan 1, 1992·European Journal of Immunology·M F Van den BroekW B Van den Berg
Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·E M SternbergR L Wilder
Apr 1, 1986·The Journal of Experimental Medicine·S M WahlA R Hand
Jan 1, 1986·Infection and Immunity·S A StimpsonJ H Schwab
Sep 1, 1973·Proceedings of the Society for Experimental Biology and Medicine·H SteinT N Harris
Aug 1, 1974·Analytical Biochemistry·O Hadzija
Oct 14, 1966·Science·W J Cromartie, J G Craddock
Jun 1, 1994·Clinical Immunology and Immunopathology·A G van de LangerijtW B van den Berg
Aug 1, 1993·The Journal of Experimental Medicine·N McCartney-FrancisS M Wahl
Aug 1, 1994·European Journal of Clinical Investigation·J E TaylorJ A Goodacre
Aug 1, 1994·The Journal of Clinical Investigation·S M WahlJ B McCarthy

❮ Previous
Next ❯

Citations

Oct 30, 2020·International Journal of Molecular Sciences·Alexandra Damerau, Timo Gaber

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Bacterial Cell Wall Structure

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.