Streptococcus pneumoniae serotype distribution in children in the Russian Federation before the introduction of pneumococcal conjugate vaccines into the National Immunization Program

Expert Review of Vaccines
Vladimir TatochenkoRalf René Reinert

Abstract

WHO recommends the inclusion of PCVs in childhood vaccination programs world-wide. Many countries including the Russian Federation are currently planning the inclusion of PCVs in their National Immunization Programs and, therefore, data on the pneumococcal serotype distribution is important to estimate the potential disease impact. Here we review eight recent epidemiological studies on the pneumococcal serotype distribution from Russia. Across all studies, serotypes 6B, 14, 19F and 23F were the most prevalent. Interestingly, serotype 3 was relatively common. Serotype 19A was prevalent among AOM, CAP and nasopharyngeal isolates and among antibiotic resistant isolates in all age groups. The differences in serotype coverage between PCV10 and PCV13 were up to 26%. Based on the current data on serotype distribution, a wide use of PCVs in Russia may lead to a significant reduction of the pneumococcal disease burden.

References

Dec 16, 1998·The Pediatric Infectious Disease Journal·T Heiskanen-KosmaM Leinonen
Jan 5, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W P HausdorffG R Siber
Jan 18, 2006·Vaccine·A E PlatonovUNKNOWN Moscow Hib Study Team
Feb 25, 2009·European Journal of Pediatrics·Manon Cevey-MacherelMario Gehri
Sep 15, 2009·Lancet·Katherine L O'BrienUNKNOWN Hib and Pneumococcal Global Burden of Disease Study Team
Dec 18, 2010·Expert Review of Vaccines·E David G McIntosh, Ralf R Reinert

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Citations

Jun 1, 2016·International Journal of Pediatric Otorhinolaryngology·Rodrigo DeAntonioJos Kleijnen
Sep 19, 2014·The Pediatric Infectious Disease Journal·Nikolay MayanskiyAlexander Baranov
Jun 21, 2016·Human Vaccines & Immunotherapeutics·Ghassan DbaiboPeter Wutzler
May 28, 2014·Human Vaccines & Immunotherapeutics·Nathalie BöhlesMichael Hensel
May 6, 2016·Human Vaccines & Immunotherapeutics·Karen CipreroLuwy Musey

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