Streptomyces buecherae sp. nov., an actinomycete isolated from multiple bat species.

Antonie van Leeuwenhoek
Paris S HammDiana E Northup

Abstract

A putative novel clade within the genus Streptomyces was discovered following antifungal screening against Pseudogymnoascus destructans, the causative agent of white-nose syndrome, and described using multi-locus sequencing analysis. Swabs from both the cave myotis bat (Myotis velifer) and the Brazilian free-tailed bat (Tadarida brasiliensis) in southern New Mexico bore isolates AC536, AC541T and AC563, which were characterised using phylogenetic, morphological, and phenotypic analyses. Multi-locus sequence analysis positions AC541T with neighbors Streptomyces rubidus (NRRL B-24619T), Streptomyces guanduensis (NRRL B-24617T), and Streptomyces yeochonensis (NRRL B-24245T). A complete genome of the type strain was assembled to determine its taxonomy and secondary metabolite potential. ANI comparisons between all closely related types strains are shown to be well below the 95-96% species delineation. DNA-DNA relatedness between AC541T and its nearest neighbors ranged between 23.7 and 24.1% confirming novelty. Approximately 1.49 Mb or 17.76% of the whole genome is devoted to natural product biosynthesis. The DNA G + C content of the genomic DNA of the type strain is 73.13 mol %. Micromorphology depicts ovoid spores with smooth surf...Continue Reading

References

Oct 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Michael Richter, Ramon Rosselló-Móra
Dec 15, 2010·BMC Bioinformatics·Keith A Jolley, Martin C J Maiden
Jul 26, 2012·PLoS Pathogens·David S Blehert
Dec 18, 2016·Applied and Environmental Microbiology·Paris S HammAndrea Porras-Alfaro
Jan 1, 2017·Antonie van Leeuwenhoek·David P LabedaWilliam W Metcalf
Feb 17, 2017·Antonie van Leeuwenhoek·Seok-Hwan YoonJongsik Chun
May 4, 2018·Molecular Biology and Evolution·Sudhir KumarKoichiro Tamura
Apr 30, 2019·Nucleic Acids Research·Kai BlinTilmann Weber

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Citations

Sep 5, 2021·Antonie van Leeuwenhoek·Achararak NammaliChitti Thawai

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Datasets Mentioned

BETA
CP060404
JACOFO01

Methods Mentioned

BETA
single hybrid
five hybrid

Software Mentioned

MEGA X
MEGA
BLAST
CD
BioNJ
Genomics
antiSMASH
BIGSdb
OrthoANI
CLC Genomics Workbench

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