Streptomyces from traditional medicine: sources of new innovations in antibiotic discovery

Journal of Medical Microbiology
Gerry A QuinnIbrahim M Banat

Abstract

Given the increased reporting of multi-resistant bacteria and the shortage of newly approved medicines, researchers have been looking towards extreme and unusual environments as a new source of antibiotics. Streptomyces currently provides many of the world's clinical antibiotics, so it comes as no surprise that these bacteria have recently been isolated from traditional medicine. Given the wide array of traditional medicines, it is hoped that these discoveries can provide the much sought after core structure diversity that will be required of a new generation of antibiotics. This review discusses the contribution of Streptomyces to antibiotics and the potential of newly discovered species in traditional medicine. We also explore how knowledge of traditional medicines can aid current initiatives in sourcing new and chemically diverse antibiotics.

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Citations

Mar 7, 2021·Microorganisms·Olga TsypikAndreas Bechthold
Apr 4, 2021·Microorganisms·Mohamad Syazwan NgalimatMohd Termizi Yusof
Jun 8, 2021·Computational and Structural Biotechnology Journal·Carlos Molina-SantiagoDiego Romero
Sep 14, 2021·Microbiology·Agustina UndabarrenaJana K Schniete
Oct 16, 2021·Critical Reviews in Microbiology·José Sebastián Dávila CostaCintia Mariana Romero

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Methods Mentioned

BETA
amidation

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