Streptomyces monashensis sp. nov., a novel mangrove soil actinobacterium from East Malaysia with antioxidative potential

Scientific Reports
Jodi Woan-Fei LawLearn-Han Lee

Abstract

A new Streptomyces species discovered from Sarawak mangrove soil is described, with the proposed name - Streptomyces monashensis sp. nov. (strain MUSC 1JT). Taxonomy status of MUSC 1JT was determined via polyphasic approach. Phylogenetic and chemotaxonomic properties of strain MUSC 1JT were in accordance with those known for genus Streptomyces. Based on phylogenetic analyses, the strains closely related to MUSC 1JT were Streptomyces corchorusii DSM 40340T (98.7%), Streptomyces olivaceoviridis NBRC 13066T (98.7%), Streptomyces canarius NBRC 13431T (98.6%) and Streptomyces coacervatus AS-0823T (98.4%). Outcomes of DNA-DNA relatedness between strain MUSC 1JT and its closely related type strains covered from 19.7 ± 2.8% to 49.1 ± 4.3%. Strain MUSC 1JT has genome size of 10,254,857 bp with DNA G + C content of 71 mol%. MUSC 1JT extract exhibited strong antioxidative activity up to 83.80 ± 4.80% in the SOD assay, with significant cytotoxic effect against colon cancer cell lines HCT-116 and SW480. Streptomyces monashensis MUSC 1JT (=DSM 103626T = MCCC 1K03221T) could potentially be a producer of novel bioactive metabolites; hence discovery of this new species may be highly significant to the biopharmaceutical industry as it could lead...Continue Reading

References

Oct 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·P G Guilfoile, C R Hutchinson
Sep 1, 1995·Chemistry & Biology·M Tomasz
Jan 14, 2003·The Journal of Antibiotics·Ratnakar N AsolkarHartmut Laatsch
Mar 20, 2004·Nature Reviews. Drug Discovery·Kevin J BarnhamAshley I Bush
Jan 18, 2005·International Journal of Systematic and Evolutionary Microbiology·Jee Yeon LeeByung Kook Hwang
Jun 9, 2005·Current Opinion in Microbiology·Lixin ZhangJun Kuai
Jun 25, 2005·Bioinformatics·Tim J CarverJulian Parkhill
Oct 1, 1985·Applied and Environmental Microbiology·A Gallois, P A Grimont
Apr 1, 1996·Applied and Environmental Microbiology·F C Pollak, R G Berger
Oct 1, 1943·Journal of Bacteriology·S A Waksman, A T Henrici
Jun 1, 1958·Proceedings of the National Academy of Sciences of the United States of America·S A WaksmanL C Vining
Dec 6, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Yu YuDes R Richardson
Dec 8, 2006·The Biochemical Journal·Barry Halliwell
Dec 29, 2006·Chemistry & Biodiversity·Jeroen S DickschatStefan Schulz
Jan 16, 2007·International Journal of Systematic and Evolutionary Microbiology·Johan GorisJames M Tiedje
Apr 25, 2007·Nucleic Acids Research·Karin LagesenDavid W Ussery
Jul 27, 2007·Natural Product Reports·Stefan Schulz, Jeroen S Dickschat
Aug 12, 2008·Drug Discovery Today·Alan L Harvey
Nov 22, 2008·Trends in Biotechnology·Philip G Williams
Feb 27, 2009·International Journal of Systematic and Evolutionary Microbiology·Jun XuJi-Sheng Ruan
Aug 25, 2009·International Journal of Systematic and Evolutionary Microbiology·B J TindallP Kämpfer
Oct 22, 2009·Natural Product Reports·Markus NettBradley S Moore
Mar 10, 2010·BMC Bioinformatics·Doug HyattLoren J Hauser
Apr 15, 2010·Marine Drugs·Sheila Marie Pimentel-ElardoUte Hentschel
Sep 16, 2010·Free Radical Biology & Medicine·Simone ReuterBharat B Aggarwal
Oct 1, 2010·Bioorganic & Medicinal Chemistry Letters·Ling DingChristian Hertweck
Mar 10, 2011·The Journal of Antibiotics·Dao-jing ZhangYuan-guang Li
Apr 26, 2011·International Journal of Systematic and Evolutionary Microbiology·Huo HuKui Hong
May 26, 2011·Natural Product Reports·Gilles P van Wezel, Kenneth J McDowall
Jul 19, 2012·World Journal of Microbiology & Biotechnology·Learn-Han LeeKui Hong
Aug 7, 2013·Bioprocess and Biosystems Engineering·G SathiyanarayananJoseph Selvin
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Jan 11, 2014·International Journal of Systematic and Evolutionary Microbiology·Learn-Han LeeKok-Gan Chan
Jan 23, 2014·International Journal of Systematic and Evolutionary Microbiology·Learn-Han LeeKok-Gan Chan
Feb 8, 2014·International Journal of Systematic and Evolutionary Microbiology·Mincheol KimJongsik Chun
Jul 6, 2014·International Journal of Systematic and Evolutionary Microbiology·Learn-Han LeeKok-Gan Chan

❮ Previous
Next ❯

Citations

Jan 18, 2020·International Journal of Systematic and Evolutionary Microbiology·Peng ZhuYongyan Liao
Jul 19, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jeysson Sánchez-SuárezLuis Díaz
Jul 10, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Feina LiChenghang Sun
Apr 8, 2020·BioMed Research International·Hefa Mangzira KemungBey-Hing Goh
Sep 6, 2020·Molecular Biology Reports·Prateek KumarMonisha Khanna Kapur
Nov 21, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jodi Woan-Fei LawLearn-Han Lee
Jul 3, 2021·Antibiotics·Martha Lok-Yung HuiLearn-Han Lee

❮ Previous
Next ❯

Datasets Mentioned

BETA
KP998432
MLYO00000000

Methods Mentioned

BETA
environmental stresses
ABTS
PCR
scanning electron microscopy

Software Mentioned

MEGA
AntiSMASH
SPSS
Artermis Comparison Tool ( ACT )
CLC Genomic Workbench
Prodigal
BLAST
CLUSTAL
RNAmmer
tRNAscan SE

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.